The expression of the CREB gene may function as a switch to regulate fear and extinction learning. The findings could provide a new avenue of treatment for PTSD and other mental health disorders. Read More
Researchers report estrogen may play a significant role in synaptic plasticity and memory formation. The study reports mice whose neurons did not produce estrogen have impairments in spatial reference memories, recognition and contextual fear memories. Restoring estrogen levels assisted in reversing the memory impairments, the study revealed. Read More
A new study reports increased levels of STEP in the hippocampus is linked to mild cognitive impairment. Read More
Researchers have identified a compound that appears to enhance long term memory. Read More
A new study explores how neural activity influences CREB dynamics. Read More
According to a new study, mice determined to have poor learning ability appeared be become better learners after being fed cinnamon. Read More
Researchers discover the basis for how animals balance risk taking and learning to get a more predictable environment. Read More
Researchers have identified genes involved in long term memory in c.elegans. Read More
The loss of fat metabolizing protein PPARalpha in the hippocampus can lead to dementia, a new study finds. Read More
Researchers identify a molecular pathway which accelerates the time taken for antidepressants to work in mouse models. Read More
Buphenyl (sodium phenylbutyrate), a medication approved for the treatment of hyperammonemia, could help prevent the progression of Alzheimer's disease, a new study finds. Read More
Researchers discover that an enzyme known for generating toxic brain plaques in Alzheimer's disease also causes additional memory and cognitive deficits via a separate mechanism. They found that BACE1 disrupts the cell's production of other molecules required for PKA function. By that mechanism, BACE1 inactivates PKA and therefore inhibits memory formation in mice, even in the absence of neurotoxic β-amyloid. Read More
