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cocaine addiction

·April 9, 2020·4 min read

Novel role for dopamine that impacts gene expression related to cocaine abuse discovered

Reducing H3Q5dop in rat models of cocaine withdrawal significantly reversed cocaine mediated gene expression changes and reduced cocaine-seeking behaviors.

Featured Neuroscience

·January 15, 2020·5 min read

Surprising effects of oxytocin on cocaine addiction

In men with a history of childhood trauma, oxytocin reduced the activity within the amygdala and cravings for cocaine. Women who were addicted to cocaine and had experienced childhood trauma showed an increase in amygdala activity following exposure to oxytocin.

Featured Genetics Neuroscience

·September 2, 2019·3 min read

Chronic cocaine use modifies gene expression

Chronic cocaine use alters the epigenetic profile of the FosB gene in the hippocampus. These alterations are required for cocaine-dependent gene expression and cocaine environment associations. Modification of hippocampal FosB results in a condition critical for cocaine-related learning.

This shows a teen sitting against a wall

Featured Neuroscience Psychology

·April 8, 2019·2 min read

Performance-enhancing drugs may increase risk of teen cocaine abuse

Teens who use anabolic steroids are at increased risk of cocaine use disorder, researchers report.

Featured Neuroscience Open Neuroscience Articles Psychology

·January 22, 2019·4 min read

Erasing Memories Associated with Cocaine Use Reduces Drug Seeking Behavior

Disrupting memories associated with environmental cues significantly reduces cocaine seeking behaviors in rat models of addiction, a new study reports.

Featured Neuroscience Psychology

·January 10, 2019·5 min read

Disconnect Between Dopamine System and Cocaine Addiction Uncovered

Researchers report the release of dopamine alters when working to obtain cocaine. The study reports, the more effort it takes to secure a supply of the illicit drug, the lower the release of dopamine when taking cocaine.

Featured Neuroscience Psychology

·January 8, 2019·3 min read

Neural Fingerprints ID Those Likely to Abstain from Cocaine

Using deep learning technology in combination with neuroimaging data, researchers were able to accurately predict who would abstain from cocaine during treatment for addiction.

Featured Genetics Neuroscience

·September 17, 2018·5 min read

Gene Therapy Via Skin Protects Mice From Lethal Cocaine Doses

Using CRISPR gene editing techniques, researchers create modified skin grafts that rapidly degrade cocaine and reduce drug seeking behaviors in mouse models of addiction.

Featured Neuroscience Open Neuroscience Articles Psychology

·September 2, 2018·4 min read

Bile Acids Reduce Cocaine Reward

Using mouse models, researchers found bile diversion surgery reduced cocaine induced increases in dopamine release and cocaine related behaviors. Researchers believe bariatric surgery or the consumption of a synthetic bile drug may help curb cocaine addiction in humans.