A new study might help to explain why people continue to take drug, even though they are aware of the negative consequences and why they find their behavior so hard to change.
Disrupting memories associated with environmental cues significantly reduces cocaine seeking behaviors in rat models of addiction, a new study reports.
Researchers have successfully tested a new vaccine in primates to battle cocaine addiction. Using neuroimaging techniques, they demonstrated the vaccine prevents cocaine from reaching the brain and producing a dopamine induced high. Human trials could begin within the next year.
Using deep learning technology in combination with neuroimaging data, researchers were able to accurately predict who would abstain from cocaine during treatment for addiction.
Manipulating the activity of Activin receptors could decrease relapse behaviors in cocaine addiction, a new study suggests.
Using CRISPR gene editing techniques, researchers create modified skin grafts that rapidly degrade cocaine and reduce drug seeking behaviors in mouse models of addiction.
Astrocytes respond to cocaine exposure in the brains of mice by promoting the formation of new synapses.
A new study reveals chronic cocaine users have a global impairment of the ventromedial prefrontal cortex.
Researchers discover the role protein mGluR5 plays in cocaine addiction. The finding could help point a way to new treatments for addiction.
Blocking M2Rs muscarinic acetylcholine receptors in the lateral habenula with an experimental drug increased cocaine-seeking behaviors in rat models of impulsive behaviors.
A new study reports mice lacking the Maged1 gene are unable to acquire an addiction to cocaine.
Silencing pyramidal neurons in the infralimbic cortex made rats more likely to relapse than those that underwent withdrawal from cocaine. The findings support growing evidence that the infralimbic cortex plays a vital role in suppressing addictive behaviors.