A new study might help to explain why people continue to take drug, even though they are aware of the negative consequences and why they find their behavior so hard to change.
Researchers report those addicted to cocaine may have difficulty controlling their addiction because of a 'back door' into the brain that circumvents their self control.
A newly created protein can modify brain activity and memory in targeted ways without the use of chemicals or drugs, a new study reports.
Astrocytes respond to cocaine exposure in the brains of mice by promoting the formation of new synapses.
Researchers discover a new form of neurotransmission which influences the long term memory created by addictive drugs.
A new study reveals bile acids can reduce the rewarding properties of cocaine use.
Using mouse models, researchers found bile diversion surgery reduced cocaine induced increases in dopamine release and cocaine related behaviors. Researchers believe bariatric surgery or the consumption of a synthetic bile drug may help curb cocaine addiction in humans.
According to a new study, women who abuse stimulant drugs have significantly less gray matter volume in brain areas vital for decision making and emotion.
A new study will investigate whether psilocybin can help curb cocaine addiction. Researchers are currently seeking people with a history of cocaine abuse to participate in the study.
Chronic cocaine use alters the epigenetic profile of the FosB gene in the hippocampus. These alterations are required for cocaine-dependent gene expression and cocaine environment associations. Modification of hippocampal FosB results in a condition critical for cocaine-related learning.
A new study reveals chronic cocaine users have a global impairment of the ventromedial prefrontal cortex.
Researchers have successfully tested a new vaccine in primates to battle cocaine addiction. Using neuroimaging techniques, they demonstrated the vaccine prevents cocaine from reaching the brain and producing a dopamine induced high. Human trials could begin within the next year.