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chronic pain

Featured Neurology Neuroscience Open Neuroscience Articles Pain

·May 19, 2020·5 min read

Mapping the weather patterns affecting people with chronic pain

A new study confirms a link between the severity of symptoms for those with chronic pain and atmospheric weather conditions. Low atmospheric pressure was associated with more severe symptoms of pain.

Featured Neurology Pain

·April 30, 2020·2 min read

A potential treatment for chronic pain

A newly developed peptide called Tat-P4-(C5)2 is targets and only affects nerve changes that pose a problem resulting in chronic pain. Previous studies have also shown the peptide can also reduce addiction.

Featured Neurology Neuroscience Pain

·March 31, 2020·3 min read

New insights into pain signaling in the brain

Study reveals how a neuropeptide called Big Dynorphin binds to the acid-sensing ion channel receptor, causing pain signals to be sent around the body.

Featured Neurology Neuroscience Open Neuroscience Articles Pain

·March 23, 2020·2 min read

Using cannabinoids to treat acute pain

Meta-analysis of previous studies reveals cannabinoid treatments produce a small, but significant reduction in subjective pain scores for sufferers of chronic pain.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 16, 2020·2 min read

A new strategy for the management of inflammatory pain

M2 macrophages can produce various endogenous opioids, such as endorphins, enkephalin, and dynorphin, which activate opioid receptors at the site of inflammation.

Featured Neurology Neuroscience

·January 5, 2020·3 min read

Early prevention of neuropathic pain

Intercepting CCL2 with specific antibodies may provide an early intervention for chronic neuropathic pain.

Featured Neurology Neuroscience Pain

·October 10, 2019·6 min read

Brain mechanisms have potential to block arthritis pain

Researchers discover the amygdala is a critical site of action for pain modulation. An existing compound, LY379268, provides pain-relieving effects and helps to reduce anxiety.

Electrophysiology Featured Neurology Neuroscience Pain Psychology

·September 26, 2019·4 min read

Molecular link between chronic pain and depression revealed

Inhibitory inputs to the neural circuit between the dorsolateral bed nucleus of the stria terminalis (dlBNST) to the ventral tegmental area (VTA) increase when a person is in chronic pain. This alteration is mediated by enhanced corticotropin-releasing factor signaling within the dlBNST, leading to suppression of the mesolimbic dopaminergic system. The result is depressive mood and anhedonia associated with chronic pain.

Featured Neurology Neuroscience Pain

·August 22, 2019·6 min read

Scorpion toxin that targets ‘wasabi receptor’ may help solve mystery of chronic pain

WaTx, a short protein in the venom of Australian Black Rock scorpions, is helping researchers uncover new information about chronic pain and inflammation.

Featured Neurology Neuroscience Pain

·June 11, 2019·3 min read

Promising treatment option for Complex Regional Pain Syndrome

Blocking the activity of interleukin-1 in mouse models of complex regional pain syndrome (CRPS) helped reverse symptoms. Researchers say patients with CRPS should respond to immune-based treatments which reduce some of the disease features.

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Featured Neurology Neuroscience Pain

·June 4, 2019·5 min read

Opioids are not sleep aids, and can actually worsen sleep research finds

Opioids are often prescribed to help those with chronic pain manage sleep problems associated with their condition. New research reports opioids effect on sleep quality is limited and of poor quality. Additionally, opioids can increase the risk of sleep apnea.