Chronic pain in mice activates Tiam1 in pyramidal neurons in the anterior cingulate cortex, increasing the number of dendritic spines and inducing synaptic plasticity. Ketamine's antidepressant effect in chronic pain is mediated by the drug blocking Tiam1-dependent maladaptive synaptic plasticity in ACC neurons.
Study reveals almost one-third of chronic pain patients use cannabis to help manage their symptoms.
Following a stroke, chronic pain can alter body perception and trick the brain into believing the affected hand is a different size. This increases the risk of accidents.
Increased daily television viewing is significantly associated with an increase in bodily and chronic pain severity over time, especially for those with Type 2 Diabetes.
People who experience chronic pain during middle age report poorer mental and overall health problems later in life.
A new study will explore the genesis of pain on a molecular and cellular level, with the goal of finding new treatments for chronic pain conditions.
Using eyeglasses that filter a specific wavelength on the green light spectrum reduces pain-related anxiety and could decrease the need for opioids for those with fibromyalgia and other chronic pain conditions.
Researchers are developing a monthly monoclonal antibody therapy for the treatment and management of chronic pain. The hope is this new therapy can replace opioids for pain management.
Repurposing drugs used in the treatment of lung cancer could offer hope for symptom relief for patients suffering from chronic pain.
Combining electrical stimulation with sounds that activate the somatosensory cortex could help bring relief to those suffering from chronic pain and other neurological conditions.
A newly developed method called sensorimotor retraining appears to be effective at treating chronic back pain.
Centralized sensation, or abnormal pain processing in the brain and spinal cord, may be an important underlying factor complicating the treatment of chronic pain in those with opioid use disorder.