FeaturedNeurologyNeurosciencePain·September 1, 2021·4 min readA Better Understanding of Chronic PainBrinker-related transcription regulators play a key role in the formation of nociceptive sensation and could be a new target for pain-relieving medications.Read More
FeaturedNeurologyNeuroscience·December 13, 2022·3 min readA Handy Lesson About Pain and the Brain in Stroke SurvivorsFollowing a stroke, chronic pain can alter body perception and trick the brain into believing the affected hand is a different size. This increases the risk of accidents.Read More
FeaturedNeurologyNeurosciencePain·June 3, 2021·4 min readA Natural Treatment for Chronic PainConolidine, a natural pain killer derived from the pinwheel flower and frequently used in Chinese medicine, interacts with a newly identified opioid receptor that regulates natural opioid peptides produced in the brain.Read More
FeaturedNeurologyNeurosciencePain·March 4, 2021·4 min readA New Cell Type Implicated in Chronic Pain and InflammationMRC1+ macrophages are dysfunctional in animal models of neuropathic pain. Stimulating the expression of the anti-inflammatory protein CD163 reduced signs of neuroinflammation in the spinal cords of mice with neuropathic pain.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·March 16, 2020·2 min readA new strategy for the management of inflammatory painM2 macrophages can produce various endogenous opioids, such as endorphins, enkephalin, and dynorphin, which activate opioid receptors at the site of inflammation.Read More
FeaturedNeurology·April 4, 2016·3 min readA Potential New Source for Pain InhibitionResearchers have uncovered a neurological mechanism that may contribute to the reduction of chronic pain.Read More
FeaturedNeurologyPain·April 30, 2020·2 min readA potential treatment for chronic painA newly developed peptide called Tat-P4-(C5)2 is targets and only affects nerve changes that pose a problem resulting in chronic pain. Previous studies have also shown the peptide can also reduce addiction.Read More
FeaturedNeurologyPain·April 22, 2023·5 min readAlcohol Fuels Pain: Study Reveals Link Between Drinking and Chronic PainChronic alcohol consumption can increase sensitivity to pain through two molecular mechanisms. Researchers also identified potential new drug targets for treating alcohol-related chronic pain. Over half of people with alcohol use disorder (AUD) suffer from persistent pain, including alcoholic neuropathy. The study found that alcohol withdrawal could result in neuropathy that was not reversed by re-exposure to alcohol.Read More
FeaturedNeurologyNeurosciencePain·May 11, 2021·3 min readAmericans Are Increasingly Experiencing Chronic PainA new study reports the number of people reporting chronic pain is rising across every age group and demographic.Read More
FeaturedNeurologyNeurosciencePain·August 2, 2022·6 min readAn Effective New Treatment for Chronic Back Pain Targets the Nervous SystemA newly developed method called sensorimotor retraining appears to be effective at treating chronic back pain.Read More
FeaturedNeurologyPain·August 24, 2015·4 min readAntidepressants Reduce Neuropathic Pain by Altering Signaling Protein Levels in Nucleus AccumbensResearchers believe the newly understood mechanism could yield insights into more precise future treatments for nerve pain and depression.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·March 22, 2018·5 min readBeing Hungry Turns Off Perception of Chronic PainResearchers report the brain can suppress feelings of chronic pain when mice are hungry.Read More