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          chronic pain

          This shows a person's face.
          FeaturedNeurosciencePain
          ·April 23, 2026·7 min read

          25% of Chronic Pain Patients Show ADHD Traits

          A study of 1,000 Japanese patients reveals that undiagnosed ADHD traits may be a hidden driver behind treatment-resistant chronic pain.
          Read More
          This shows a woman rubbing her neck
          FeaturedNeurologyNeurosciencePain
          ·September 1, 2021·4 min read

          A Better Understanding of Chronic Pain

          Brinker-related transcription regulators play a key role in the formation of nociceptive sensation and could be a new target for pain-relieving medications.
          Read More
          This shows an older lady's hands
          FeaturedNeurologyNeuroscience
          ·December 13, 2022·3 min read

          A Handy Lesson About Pain and the Brain in Stroke Survivors

          Following a stroke, chronic pain can alter body perception and trick the brain into believing the affected hand is a different size. This increases the risk of accidents.
          Read More
          This shows a pinwheel flower
          FeaturedNeurologyNeurosciencePain
          ·June 3, 2021·4 min read

          A Natural Treatment for Chronic Pain

          Conolidine, a natural pain killer derived from the pinwheel flower and frequently used in Chinese medicine, interacts with a newly identified opioid receptor that regulates natural opioid peptides produced in the brain.
          Read More
          This is an illustration of the spinal cord with the cells
          FeaturedNeurologyNeurosciencePain
          ·March 4, 2021·4 min read

          A New Cell Type Implicated in Chronic Pain and Inflammation

          MRC1+ macrophages are dysfunctional in animal models of neuropathic pain. Stimulating the expression of the anti-inflammatory protein CD163 reduced signs of neuroinflammation in the spinal cords of mice with neuropathic pain.
          Read More
          This shows marcophages
          FeaturedNeurologyNeuroscienceOpen Neuroscience Articles
          ·March 16, 2020·2 min read

          A new strategy for the management of inflammatory pain

          M2 macrophages can produce various endogenous opioids, such as endorphins, enkephalin, and dynorphin, which activate opioid receptors at the site of inflammation.
          Read More
          Stick and ball model of GABA.
          FeaturedNeurology
          ·April 4, 2016·3 min read

          A Potential New Source for Pain Inhibition

          Researchers have uncovered a neurological mechanism that may contribute to the reduction of chronic pain.
          Read More
          This shows neurons
          FeaturedNeurologyPain
          ·April 30, 2020·2 min read

          A potential treatment for chronic pain

          A newly developed peptide called Tat-P4-(C5)2 is targets and only affects nerve changes that pose a problem resulting in chronic pain. Previous studies have also shown the peptide can also reduce addiction.
          Read More
          This shows a head and an inflamed brain. Overlaid is a fingerprint.
          FeaturedNeurologyNeurosciencePain
          ·March 3, 2026·8 min read

          AI Decodes the “Brain Fingerprint” of Chronic Pain

          Researchers identify personalized "pain connectomes" in the brain, proving that chronic pain can be objectively measured through precision neuroimaging.
          Read More
          This shows a man in pain
          FeaturedNeurologyPain
          ·April 22, 2023·5 min read

          Alcohol Fuels Pain: Study Reveals Link Between Drinking and Chronic Pain

          Chronic alcohol consumption can increase sensitivity to pain through two molecular mechanisms. Researchers also identified potential new drug targets for treating alcohol-related chronic pain. Over half of people with alcohol use disorder (AUD) suffer from persistent pain, including alcoholic neuropathy. The study found that alcohol withdrawal could result in neuropathy that was not reversed by re-exposure to alcohol.
          Read More
          This shows a man holding his head in pain
          FeaturedNeurologyNeurosciencePain
          ·May 11, 2021·3 min read

          Americans Are Increasingly Experiencing Chronic Pain

          A new study reports the number of people reporting chronic pain is rising across every age group and demographic.
          Read More
          This shows a woman's back
          FeaturedNeurologyNeurosciencePain
          ·August 2, 2022·6 min read

          An Effective New Treatment for Chronic Back Pain Targets the Nervous System

          A newly developed method called sensorimotor retraining appears to be effective at treating chronic back pain.
          Read More
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          A 3D digital rendering showing a developing fetal brain connected by glowing neural pathways and floating DNA strands, surrounded by subtle immune cells.

          How Severe Illness During Pregnancy Alters Fetal Brain Development

          A 3D digital illustration of a human brain side-by-side comparison, highlighting the language centers glowing brightly and equally in both a younger and older brain, while executive function areas are dimmed in the older brain.

          Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

          Rejuvenation of Microglia by Youth Protein TIMP2 in the Aging Brain

          Youth Protein TIMP2 Restores Immune Function in the Aging Brain

          A multi-panel documentary photo. Left: A Black man sits alone on a locker room bench with his head down. Center: A Latino man sits withdrawn at a family kitchen table. Right: A White man looks thoughtfully at wellness pamphlets in a public waiting area. All convey isolation.

          Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

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