A specific anthrax toxin blocks multiple types of pain in mouse models, a new study reports.
Genetic differences contribute to both an increased risk of certain types of chronic pain and a reduction in the size of specific brain regions.
Those with a genetic predisposition to clinical depression are more likely to exhibit physical symptoms including migraines, chronic pain, and fatigue, researchers report.
A four-week course of pain reprocessing therapy (PRT) provided up to 12 months of relief from pain for chronic pain sufferers. Additionally, the psychological treatment program altered brain networks associated with pain processing.
Brinker-related transcription regulators play a key role in the formation of nociceptive sensation and could be a new target for pain-relieving medications.
Widespread pain, a subset of chronic pain associated with musculoskeletal disorders, is linked to an increased risk of all types of dementias, including Alzheimer's disease, and a greater risk of stroke.
A Western-style diet, high in omega-6 polyunsaturated fats, increases symptoms of inflammation, neuropathy, and chronic pain. However, changing to a lower-fat diet can help reverse or relieve symptoms of inflammatory pain disorders.
Conolidine, a natural pain killer derived from the pinwheel flower and frequently used in Chinese medicine, interacts with a newly identified opioid receptor that regulates natural opioid peptides produced in the brain.
A new study reports the number of people reporting chronic pain is rising across every age group and demographic.
Study reveals there is no significant uptick in men who played high school football reporting problems with brain health in middle age compared to their peers who did not play sports. However, ex-football players were more likely to experience sleep problems and be prescribed medications for chronic pain during mid-life.
Genetics may help explain why women are at higher risk for developing chronic pain disorders than men. The study also sheds light on the role the central nervous system plays in the development of chronic pain.
MRC1+ macrophages are dysfunctional in animal models of neuropathic pain. Stimulating the expression of the anti-inflammatory protein CD163 reduced signs of neuroinflammation in the spinal cords of mice with neuropathic pain.
