Early prevention of neuropathic pain
Intercepting CCL2 with specific antibodies may provide an early intervention for chronic neuropathic pain.... Read More...
chronic pain
Brain mechanisms have potential to block arthritis pain
Researchers discover the amygdala is a critical site of action for pain modulation. An existing compound, LY379268, provides pain-relieving effects and helps to reduce anxiety.... Read More...
Molecular link between chronic pain and depression revealed
Inhibitory inputs to the neural circuit between the dorsolateral bed nucleus of the stria terminalis (dlBNST) to the ventral tegmental area (VTA) increase when a person is in chronic pain. This alteration is mediated by enhanced corticotropin-releasing factor signaling within the dlBNST, leading to suppression of the mesolimbic dopaminergic system. The result is depressive mood and anhedonia associated with chronic pain.... Read More...
Scorpion toxin that targets ‘wasabi receptor’ may help solve mystery of chronic pain
WaTx, a short protein in the venom of Australian Black Rock scorpions, is helping researchers uncover new information about chronic pain and inflammation. ... Read More...
Promising treatment option for Complex Regional Pain Syndrome
Blocking the activity of interleukin-1 in mouse models of complex regional pain syndrome (CRPS) helped reverse symptoms. Researchers say patients with CRPS should respond to immune-based treatments which reduce some of the disease features.... Read More...
Opioids are not sleep aids, and can actually worsen sleep research finds
Opioids are often prescribed to help those with chronic pain manage sleep problems associated with their condition. New research reports opioids effect on sleep quality is limited and of poor quality. Additionally, opioids can increase the risk of sleep apnea.... Read More...
Experimental blood test accurately spots fibromyalgia
A new biomarker for fibromyalgia has been identified in blood samples taken from patients suffering from the condition. ... Read More...
New Target for Chronic Pain Relief Confirmed by Scientists
A research group at Hiroshima University observed a potential new target for chronic pain treatment. Further research using this receptor could lead to new, more effective drugs to use in pain-relieving treatment for chronic pain.... Read More...
Breakthrough in Developing Blood Test for Pain
Researchers have identified biomarkers in the blood which can help determine the severity of a person's pain level. The findings could help doctors to accurately measure pain and stem the opioid crisis.... Read More...
The Brain Cells That Make Pain Unpleasant Identified
Researchers report the sensation and emotional experiences of pain are not the same. A new study reveals neurons in the amygdala responsible for negative emotions associated with chronic pain. ... Read More...
Pain and Substance Abuse Interact in a Vicious Cycle
Being in pain and taking illicit substances can lead to a vicious cycle that ultimately worsens and maintains both addiction and pain. ... Read More...
Men and Women Remember Pain Differently
A new study reports males seem to remember experiences of pain more clearly, while females are less stress by previous painful experiences. Researchers injected ZIP, a memory blocker into the brains of mice before a painful experience. Following the treatment, the males showed no signs of remembering the pain. The study suggests chronic pain is a problem to the extent you remember it. The findings could help develop new treatments for chronic pain.... Read More...