Elevated levels of LDL cholesterol has been linked to an increased risk of early-onset Alzheimer's disease, in those with and without a genetic risk factor. This suggests cholesterol could be an independent risk factor for dementia. Additionally, researchers identified a potential new genetic risk factor for early-onset Alzheimer's, a rare variant of the APOB gene.
Consuming too much omega 6 during pregnancy has been linked to an increased risk of neurodevelopmental issues in babies and pregnancy complications. In mice who had higher levels of linoleic acid in their diets, researchers noted altered concentrations of inflammatory proteins and a decrease in hormones that regulate fetal growth and development. Researchers stress the effects of a high linoleic acid concentration in diet are the same for both animal models and humans.
The common statin drug Simvastatin reduces brain atrophy and slows the progression of secondary progressive multiple sclerosis (SPMS). The effects appear to be independent of the drug's cholesterol-lowering effects.
Study finds a 'peculiar association' between amyloid precursor protein and cholesterol in the cell membrane of synapses. Amyloid precursor protein may contribute to cholesterol deficiency, triggering neurodegeneration in Alzheimer's disease.
Low levels of LDL cholesterol and triglycerides have been linked to an increased risk of hemorrhagic stroke in women.
DIPG cancer cells exposed to MI-2 fail to maintain healthy levels of cholesterol and die quickly, by inhibiting lanosterol synthase. Additionally, while MI-2 destroys glioma cancer cells, the drug does not damage healthy brain cells.
Researchers say schizophrenia should not be considered to be just a disorder of the mind, as schizophrenia can also impact other organs. A new study reveals people with schizophrenia often have an over active immune system and other physical disorders.
University of Cambridge researchers report cholesterol may play a role in the onset of Alzheimer's disease. Researchers discovered cholesterol can trigger amyloid beta to aggregate, which can lead to neuron death.
Taking steps to improve your heart health early in life can help prevent brain shrinkage as you age, a new Neurology study reports. Researchers discovered people who had better heart health scores also had a higher average brain volume as a percentage of their total head size in middle age.