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cholesterol

·November 11, 2024·6 min read

Fluctuating Cholesterol Linked to Higher Dementia Risk

Older adults with significant fluctuations in cholesterol levels are at increased risk for dementia and cognitive decline, even without medication changes. Researchers studied nearly 10,000 older adults, tracking their cholesterol levels and cognitive function over six years. High variability in total and LDL ("bad") cholesterol was associated with a 60% increase in dementia and 23% increase in cognitive decline.

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·January 9, 2017·4 min read

High Cholesterol Intake and Eggs Do Not Increase Risk of Memory Disorders

A new study reports there appears to be no link between a high intake of dietary cholesterol and an increased risk of dementia, even in those who carried the APOE4 gene.

Featured Neurology Neuroscience

·May 28, 2019·6 min read

High LDL cholesterol linked to early-onset Alzheimer’s

Elevated levels of LDL cholesterol has been linked to an increased risk of early-onset Alzheimer's disease, in those with and without a genetic risk factor. This suggests cholesterol could be an independent risk factor for dementia. Additionally, researchers identified a potential new genetic risk factor for early-onset Alzheimer's, a rare variant of the APOB gene.

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·October 16, 2015·4 min read

Astrocytes Could Hold the Clue to ALS

According to researchers, astrocytes lose the ability to support motor neurons as ALS progresses.

This is a cartoon of a heart and a brain

Featured Neurology Neuroscience

·October 21, 2019·3 min read

What’s good for the heart is good for the brain

Twin study reveals higher cardiovascular health is associated with better cognitive health.

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·April 23, 2019·4 min read

Scientists propose new theory on Alzheimer’s, amyloid connection

Study finds a 'peculiar association' between amyloid precursor protein and cholesterol in the cell membrane of synapses. Amyloid precursor protein may contribute to cholesterol deficiency, triggering neurodegeneration in Alzheimer's disease.

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·August 14, 2021·5 min read

Brain Cholesterol Regulates Alzheimer’s Plaques

A new advanced imaging technique shows how cholesterol regulates the production of Alzheimer's associated amyloid beta proteins in astrocytes.

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·June 3, 2019·4 min read

Antidepressants could be used to treat multiple bacterial infections

FIASMA antidepressants, such as amitriptyline and desipramine, halt the growth of four different kinds of bacterial pathogens in cell cultures and animal models. The antidepressants have shown to be effective in killing intracellular bacteria in two chlamydia infections, as well as human granulocytic anaplasmosis, a tick-borne disease that attacks white blood cells.

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·October 4, 2016·5 min read

Alzheimer’s Linked Protein Can Be Removed From Brain Without Hindering Memory and Learning

Researchers report mice can retain their memories and ability to learn when almost all ApoE is removed from the brain but kept present in the liver to filter cholesterol.

Featured Neuroscience Open Neuroscience Articles

·May 14, 2022·5 min read

Drinker’s Sex Plus Brewing Method May Be Key to Coffee’s Link to Raised Cholesterol

The sex of the drinker in addition to the brewing method may explain coffee's link to increased cholesterol. Drinking 3-5 cups of espresso per day increased serum total cholesterol, especially in males.

Featured Neurology Neuroscience

·July 19, 2017·3 min read

Healthy Heart in 20s Means Healthy Brain in 40s

Taking steps to improve your heart health early in life can help prevent brain shrinkage as you age, a new Neurology study reports. Researchers discovered people who had better heart health scores also had a higher average brain volume as a percentage of their total head size in middle age.