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brain organoids

This shows a cross section of the rat brain

·October 12, 2022·4 min read

Transplanting Human Neurons in Rat Brains Sheds New Light on Brain Development

By transplanting living brain cells from an organoid into newborn rats, researchers create a new method of studying neurodevelopment and show neurons from one species can effectively form connections with another.

This shows different brain cells in the origanoid

Featured Neuroscience

·October 12, 2022·7 min read

Human Brain Cells in a Dish Learn to Play Pong

Brain cells grown in a petri dish can perform goal-directed tasks, such as learning to play a game of Pong.

Featured Genetics Neuroscience

·October 7, 2022·6 min read

Mapping Human Brain Development

Brain organoids are helping researchers map the molecular, genetic, and structural changes that occur during brain development.

This shows an organoid cerebral cortex slice

Autism Featured Neuroscience Open Neuroscience Articles

·October 6, 2022·5 min read

Brain Organoids Provide a Window Into Autism

Investigating the effects of genetic abnormalities associated with autism and human brain development, researchers found brain organoids engineered to have lower levels of the ASD-associated SHANK3 gene had distinct features including neural firing hyperactivity, disruptions in pathways that cause cells to adhere to each other, and indications of ineffective neurotransmission.

Featured Genetics Neuroscience

·September 29, 2022·6 min read

Making Lab-Grown Brain Organoids ‘Brainier’

A new study offers guidelines and methods for consistently generating high-quality, well-structured brain organoids.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·May 2, 2022·5 min read

Gene Therapy Reverses Effects of Autism-Linked Mutation in Brain Organoids

A brain organoid study reveals how a genetic mutation associated with Pitt-Hopkins syndrome, a profound form of autism, disrupts neural development. Using gene-editing technology, researchers recovered the function of the TCF4 gene and effectively restored neural structure and function.

This shows a model of a head and a brain

Featured Neuroethics Neuroscience

·February 18, 2022·4 min read

The Ethics of Research on Conscious Artificial Brains

A new ethical framework proposes researchers should already assume brain organoids already have consciousness, rather than waiting for research to confirm they do.

Autism Featured Genetics Neuroscience

·February 2, 2022·6 min read

Different Autism Risk Genes, Same Effects on Brain Development

Three different autism risk genes affect similar aspects of neural formation and the same types of neurons in the developing human brain.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·December 16, 2021·4 min read

‘Mini-Brains’ Provide Clues About Early Life Origins of Schizophrenia

Brain organoid study reveals multiple changes in brain cells during early embryonic development may contribute to schizophrenia later in life.

This shows a numerous different graphs from the study

Featured Neurology Neuroscience Neuroscience Videos

·November 2, 2021·2 min read

Mini-Brain Models Used in Hunt for Alzheimer’s Treatment

Brain organoids can be used to study molecular mechanisms that drive brain aging and neurodegenerative disorders. The mini-brains allow for the testing of molecules that could become potential therapeutic treatment options for neurodegenerative diseases.

Featured Neuroscience

·August 23, 2021·6 min read

Brain Organoids With Complex Neural Activity Developed

Newly developed brain organoids grown from stem cells showed organized waves of neural activity similar to that seen in living human brains.

This shows amyloid beta in a staining sample

Featured Neurology Neuroscience

·August 7, 2021·3 min read

Miniature Brain Models Developed to Study the Causes of Alzheimer’s and Test Drugs in Development

Researchers have developed a new brain organoid model to study the mechanistic causes of Alzheimer's disease and test dementia drugs currently in development.

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