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brain organoids

This shows amyloid beta in a staining sample

·August 7, 2021·3 min read

Miniature Brain Models Developed to Study the Causes of Alzheimer’s and Test Drugs in Development

Researchers have developed a new brain organoid model to study the mechanistic causes of Alzheimer's disease and test dementia drugs currently in development.

Featured Neurology Neuroscience

·July 26, 2021·5 min read

Early Signs of Frontotemporal Dementia Found in Personalized Cerebral Organoids

Researchers recreated the damage seen in frontotemporal dementia in brain organoid models. The study reveals an experimental drug designed to treat Crohn's disease may help prevent neuron death associated with FTD.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·July 14, 2021·5 min read

Mini-Brain Study Shows How Environmental Risk Factors Can Amplify Genetic Risks for Autism

Using human stem cells to develop a brain organoid model, researchers were able to show exposure to a common pesticide synergizes with an autism-linked gene mutation. The study provides clear evidence that genetics and environment may combine to disrupt neurodevelopment.

Featured Genetics Neuroscience

·March 24, 2021·5 min read

How Humans Develop Larger Brains Than Other Apes

Using brain organoid models, researchers have identified how the brain grows much larger and has three times as many neurons, as the brains of chimpanzees and gorillas.

This shows a female scientist looking in a microscope

Featured Genetics Neuroscience

·February 22, 2021·4 min read

‘Mini Brain’ Organoids Grown in Lab Mature Much Like Infant Brains

Brain organoids, or mini-brains, created from human stem cells appear to develop in much the same way as a human brain. The organoids follow an internal clock that guides their maturation in sync with the timeline for human brain development.

Featured Genetics Neuroscience

·February 11, 2021·5 min read

How a Single Gene Alteration May Have Separated Modern Humans From Predecessors

By altering the NOVA1 gene, researchers were able to "Neanderthal-izes" a brain organoid model. Study reveals there is only a one gene difference between the modern human brain and that of our extinct ancestors.

This shows a man in a facemask surrounded by representations of covid-19

Featured Genetics Neurology Neuroscience

·February 4, 2021·4 min read

The Link Between ‘Alzheimer’s Gene’ and COVID-19

ApoE4, a gene associated with an increased risk of Alzheimer's disease, also appears to increase susceptibility and the severity of COVID-19. SARS-CoV-2, the virus responsible for coronavirus, increased susceptibility to COVID-19 in ApoE4 neurons and astrocytes in brain organoid models.

Featured Genetics Neuroscience Open Neuroscience Articles

·December 8, 2020·6 min read

‘SCOUT’ Helps Researchers Find, Quantify Significant Differences Among Organoids

SCOUT is a newly developed pipeline for clearing, labeling, 3D imaging, and analyzing cerebral organoids.

Featured Genetics Neuroscience Open Neuroscience Articles

·August 25, 2020·3 min read

Scientists Prove SARS-CoV-2 Potential to Infect Human Brain Organoids

SARS-CoV-2, the virus responsible for COVID-19, can infect human neural progenitor cells and brain organoids. The findings back previous research, finding coronavirus can infect the human brain.