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          brain organoids

          This shows mitochondria.
          FeaturedGeneticsNeuroscience
          ·December 14, 2024·3 min read

          Mini-Brains Reveal New Insights Into Mitochondrial Brain Disorders

          Researchers have created mini-brains to study how mitochondrial failure impacts brain cells, opening new possibilities for treating severe conditions like epilepsy. These brain organoids mimic real disease processes, allowing scientists to observe mitochondrial dysfunction and test potential treatments.
          Read More
          This shows the glioblastoma model.
          Brain CancerFeaturedNeurologyNeuroscience
          ·December 9, 2024·6 min read

          Lab-Grown Tumor Models Mirror Glioblastoma Treatment Response

          Glioblastoma organoids, lab-grown replicas of a patient’s tumor, accurately predict how the tumor responds to CAR T cell therapy. This breakthrough allows real-time testing of therapies, showing that responses in the organoid closely mirror those in the patient.
          Read More
          This shows a brain and DNA.
          AutismFeaturedNeuroscience
          ·October 24, 2024·6 min read

          Stem Cell Mini-Brains Unlock Insights into Autism

          Researchers have created "mini-brains" using stem cells from patients with a rare form of autism, allowing them to study brain development in detail. These organoids revealed how a genetic mutation in MEF2C disrupts the balance between excitatory and inhibitory neurons, leading to autism.
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          This shows neurons.
          FeaturedNeurologyNeuroscience
          ·October 15, 2024·4 min read

          Mini Brains Uncover Treatment Leads for Lewy Body Dementia

          Lewy body dementia (LBD) is a challenging-to-diagnose neurodegenerative disease with symptoms similar to both Parkinson’s and Alzheimer’s diseases, including hallucinations, cognitive issues, and movement disorders. To study LBD’s progression, researchers developed mini brain models from LBD patient stem cells, replicating key disease characteristics seen in human brains. These models helped identify four promising drugs that may inhibit alpha-synuclein buildup, a key protein associated with LBD.
          Read More
          This shows cells.
          FeaturedNeuroethicsNeuroscience
          ·June 20, 2024·4 min read

          Organoids and Embryo Models: Redefining Human Individuality?

          Advances in organoids and embryonic models raise questions about human individuality. A new study argues these models can reinforce, not weaken, the concept of human individuality when viewed through personhood and sentience frameworks. Researchers emphasize that current technologies are far from achieving personhood in embryo models or organoids. The ethical focus should remain on the wellbeing of actual persons and sentient beings.
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          This shows neurons.
          FeaturedGeneticsNeurologyNeuroscience
          ·May 14, 2024·6 min read

          Mini-Brains from Stem Cells Provide Hope for Alzheimer’s Diagnosis

          Researchers developed tiny "mini-brains" from stem cells to help diagnose and treat Alzheimer’s disease. These mini-brains, created from human blood, accurately reflect the pathology of Alzheimer’s on a smaller scale. This innovative technology could revolutionize healthcare, especially for remote communities, by providing a simpler way to diagnose neurological conditions.
          Read More
          This shows the lab grown networks.
          FeaturedNeuroscience
          ·April 10, 2024·4 min read

          Bridging Brain Circuits with Lab-Grown Neural Networks

          Researchers successfully connected lab-grown brain tissues, mimicking the complex networks found in the human brain. This novel method involves linking “neural organoids” with axonal bundles, enabling the study of interregional brain connections and their role in human cognitive functions.
          Read More
          This shows a computer chip.
          FeaturedNeuroscience
          ·December 12, 2023·4 min read

          Innovative Brain Cell Chips Unlock New Horizons in Speech Recognition

          In a revolutionary study, researchers created a hybrid system called Brainoware, which integrates human brain cell networks, or organoids, with a computer chip. This innovative setup demonstrates capabilities in processing, learning, and memory, and has achieved basic speech recognition skills by decoding audio clips of Japanese vowels.
          Read More
          This shows DNA and two heads.
          FeaturedGeneticsNeurosciencePsychology
          ·October 24, 2023·7 min read

          Novel Schizophrenia Insights from Brain Organoids and Genes

          Researchers leveraged cutting-edge technology to gain insights into schizophrenia's neurodevelopmental origins. The researchers grew brain organoids from patients' skin cells, finding persistent axonal disruptions in those with schizophrenia. In another study, researchers zeroed in on a schizophrenia risk gene, CYFIP1, revealing its potential role in brain immune cells called microglia and their influence on synaptic pruning - a crucial process for brain health.
          Read More
          This shows a brain in a dish.
          FeaturedNeuroscience
          ·July 13, 2023·5 min read

          Lab-Grown Human Brain Organoids Go Animal-Free

          Researchers have innovated a method to produce lab-grown mini brains, known as human brain organoids, free of animal cells, promising a more accurate study and treatment of neurodegenerative conditions. Previously, brain organoids were grown using a substance derived from mouse sarcomas called Matrigel, leading to inconsistencies due to its undefined composition and variability.
          Read More
          This is an AI representation of a brain organoid in a petri dish.
          FeaturedNeuroethicsNeuroscience
          ·May 9, 2023·5 min read

          Tiny Human Brain Tissue Organoids Can’t Be Legally Considered “a Person”

          Researchers proposed the need for a legal framework to guide the conversation on whether or not human brain organoids can be considered people. Brain organoids are grown from stem cells in a lab, mimicking the growth and structure of real brains.
          Read More
          This shows a brain
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·March 5, 2023·4 min read

          Real AI Will Need Biology: Computers Powered by Human Brain Cells

          The human brain continues to massively outperform AI technology in a range of tasks, a new study reports. Researchers outline their plans for biocomputers and organoid intelligence systems as future improvements for artificial intelligence technology.
          Read More
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          This shows a head.

          Brain’s Internal Disappointment Meter Forces Behavioral Change

          This shows an octopus.

          Octopuses Can Use Mirrors to Find Food

          This shows a cloudy head.

          Why the Brain Doesn’t Need Choices to Generate Intent

          This shows a book and a brain made out of paper.

          Brain Integrates Paper Book Narratives Faster Than Digital

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