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brain mapping

·June 6, 2025·7 min read

Brain Area Stores and Resolves Hypotheses for Landmark Ambiguity

Researchers have discovered that the mouse brain can simultaneously encode multiple hypotheses about its spatial location while navigating environments with ambiguous landmarks. In a complex task requiring mice to distinguish between identical cues, neurons in the retrosplenial cortex (RSC) exhibited distinct activity patterns reflecting different possibilities of where the mouse might be.

Featured Neuroscience Psychology

·June 4, 2025·4 min read

AI Model Maps Brain Dynamics to Boost Mental Health Diagnosis

A new adaptive brain modeling framework offers fresh hope for objective diagnosis of neuropsychiatric disorders, which currently lack reliable neuroimaging biomarkers. Using an enhanced version of the Landau-Stuart oscillator model, researchers simulated brain activity to better capture individual-specific neural dynamics.

Featured Neuroscience

·May 12, 2025·4 min read

First Full Map of Fruit Fly Nervous System Reveals Sex Differences

Scientists have completed the first full connectome of the adult fruit fly, including both the brain and ventral nerve cord, revealing how neural signals travel between these two structures. This breakthrough uncovers never-before-seen neurons in the neck that transmit brain commands to the body.

Featured Neuroscience

·May 11, 2025·7 min read

Brain Cells That Predict What Comes Next, Even When It’s New

A new study reveals that the brain uses special neurons to track where we are in a sequence of actions—not just where we are in space. In mice, researchers found “goal-progress cells” that fire based on how far along the animal is in a behavioral task, enabling them to infer what comes next even in novel scenarios.

Featured Neuroscience

·May 9, 2025·6 min read

Map of Sugar Receptor Could Curb Our Cravings

For the first time, scientists have mapped the 3D structure of the human sweet taste receptor, offering critical insights into how we perceive sweetness and why we crave sugar. This detailed map, created using cryo-electron microscopy, reveals how sweeteners bind to a key receptor component, TAS1R2, which resembles a Venus flytrap.

Featured Neuroscience

·May 8, 2025·7 min read

New Method Maps Brain Networks With Unprecedented Detail

A revolutionary microscopy method called LICONN enables scientists to reconstruct brain tissue and map synaptic connections using standard light microscopes. By embedding brain tissue in hydrogel, expanding it, and imaging at nanoscale resolution, researchers achieve a detailed view of neuronal architecture previously only possible with electron microscopy.

Featured Neuroscience

·May 2, 2025·4 min read

New 3D Atlas Offers Unmatched Precision in Mapping the Mouse Brain

Researchers have unveiled the Duke Mouse Brain Atlas, a cutting-edge, three-dimensional map that captures brain structures from large regions down to individual cells. Combining MRI, microCT, and light sheet microscopy, the atlas resolves imaging distortions and enables precise comparison across studies.

Featured Neuroscience

·April 28, 2025·5 min read

Brain Growth Charts Reveal Early Cognitive Development Patterns

A new study has created the first normative charts of brain functional development from birth to six years old, highlighting how brain network growth tracks with cognitive milestones. Using MRI scans from over 1,000 children, researchers mapped how different brain networks, such as visual, subcortical, and attention systems, mature and interact over time.

Featured Neuroscience

·April 9, 2025·7 min read

World’s Most Detailed Brain Map Built From a Grain of Brain Tissue

Scientists have created the most detailed wiring diagram of a mammalian brain to date, mapping every cell and synapse in a cubic millimeter of a mouse’s visual cortex. Using cutting-edge microscopy, AI, and 3D reconstruction, researchers captured more than 200,000 cells and over 500 million connections.

Featured Neuroscience

·April 1, 2025·5 min read

Brain Mapping Tool Reveals How Learning Rewires Synaptic Links

Researchers have developed DELTA, a powerful new imaging method that maps brain-wide synaptic changes during learning. By labeling synaptic proteins before and after behavioral training, scientists can now visualize where and how neural connections shift over time.

Featured Genetics Neurology Neuroscience

·March 6, 2025·4 min read

Mapping Brain Cells Vulnerable to Alzheimer’s Protein Buildup

Researchers have identified memory-related brain cells that are highly vulnerable to tau protein accumulation, a key factor in Alzheimer’s disease. Using the MISS brain-mapping technique, they profiled 1.3 million cells in mice to pinpoint which cell types are most affected.

Featured Neurology Neuroscience

·February 27, 2025·7 min read

Brain Map Reveals Early Signs of MS Before Symptoms Appear

Researchers have created a four-dimensional brain map that reveals how MS-like lesions form, providing new insights into the earliest stages of the disease. Using a marmoset model instead of mice, they tracked lesion development in real time with MRI imaging, identifying vulnerable brain regions weeks before visible damage occurred.

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brain mapping

Brain Area Stores and Resolves Hypotheses for Landmark Ambiguity

AI Model Maps Brain Dynamics to Boost Mental Health Diagnosis

First Full Map of Fruit Fly Nervous System Reveals Sex Differences

Brain Cells That Predict What Comes Next, Even When It’s New

Map of Sugar Receptor Could Curb Our Cravings

New Method Maps Brain Networks With Unprecedented Detail

New 3D Atlas Offers Unmatched Precision in Mapping the Mouse Brain

Brain Growth Charts Reveal Early Cognitive Development Patterns

World’s Most Detailed Brain Map Built From a Grain of Brain Tissue

Brain Mapping Tool Reveals How Learning Rewires Synaptic Links

Mapping Brain Cells Vulnerable to Alzheimer’s Protein Buildup

Brain Map Reveals Early Signs of MS Before Symptoms Appear

The Placenta May Decide Autism Vulnerability

Imaging Index Links Blood Flow to Cellular Architecture

Nighttime Light Exposure Linked to Sleep Loss in Schizophrenia

Eye-Blink Rate Predicts Cognitive Flexibility in Preschoolers

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