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blood-brain barrier

Featured Neuroscience

·April 17, 2020·3 min read

New nanocarrier drug delivery technology crosses the blood-brain barrier

Researchers have developed a cyclic peptide that can enhance blood-brain barrier penetration.

Featured Neurology Neuroscience Open Neuroscience Articles

·April 10, 2020·3 min read

More evidence ultrasound can help in battle against Alzheimer’s disease

Combining focused ultrasound with microbubble treatments weakens the connection between blood-brain barrier cells, effectively allowing for better delivery and absorption of drug treatments.

Featured Neuroscience Psychology

·March 14, 2020·5 min read

How chronic stress changes the brain, and what you can do to reverse the damage

Chronic stress can affect a person's health and mental well being. Due to the COVID-19 virus, chronic stress is on the rise worldwide. Researchers examine the general and psychological health implications of chronic stress and suggest some methods we can adopt to keep our stress levels in check.

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·February 28, 2020·3 min read

Our own immune cells damage the integrity of the blood-brain barrier

Microglia initially protects the blood-brain barrier from damage due to systemic inflammation. However, microglia can alter their behavior and increase the permeability of the blood-brain barrier, thus damaging it.

Featured Genetics Neuroscience Psychology

·January 21, 2020·2 min read

Treatment for depression must also restore proper functioning of the blood-brain barrier

In order to treat those with treatment-resistant depression, researchers suggest the integrity of the blood-brain barrier be restored.

This shows the chip, a brain and neurons

Brain Cancer Featured Neurology Neuroscience Neuroscience Videos

·January 4, 2020·4 min read

Buzzing Through the Blood-Brain Barrier

Neuroengineers have developed a new, non-toxic, biodegradable device that can help transport vital medications to the brain by locally opening the blood-brain barrier with ultrasound.

Featured Neurology Neuroscience

·December 29, 2019·7 min read

Drugs that quell brain inflammation reverse dementia

Older mice given anti-inflammatory medication were better able to learn new tasks and became almost as adept at learning as mice half their age.

Featured Neurology Neuroscience

·December 4, 2019·6 min read

Drugs that quell brain inflammation reverse dementia

A synthesized small-molecule drug blocks the TGF-beta receptor in astrocytes and traverses the blood-brain barrier in mice. When administered, the drug lowered receptor activity to that seen in younger mice and reduced inflammation. The aged mice were able to navigate mazes and learn spatial tasks as well as younger mice.

Featured Neuroscience

·October 22, 2019·3 min read

Exposure to environmental PCBs impairs brain function in mice

Polychlorinated biphenyls (PCBs), chemicals commonly used during the 20th century as flame retardants and in industrial products, disrupt the performance of astrocytes, leading to impaired function. Environmental exposure to PCBs could contribute to a range of neurodegenerative diseases.

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·August 28, 2019·6 min read

Robotic thread is designed to slip through the brain’s blood vessels

A newly designed thread-like robot can deliver clot reducing therapies in response to stroke or other brain blockages.

Featured Neurology Neuroscience

·July 12, 2019·3 min read

Healthy blood vessels may be the answer to Alzheimer’s prevention

Damaged capillaries in the brain may set the stage for the development of Alzheimer's disease, years before symptoms appear.

Featured Neurology Neuroscience

·June 6, 2019·5 min read

Ultrasound method restores dopaminergic pathway in brain at Parkinson’s early stages

Using transcranial focused ultrasound in combination with injectable microbubbles, researchers open a pathway through the blood-brain barrier. The technique allows drugs to penetrate the brain and trigger therapeutic effects for those with neurodegenerative diseases.