Data Sharing Uncovers Five New Risk Genes For Alzheimer’s
A new study of the genetic data from over 94,000 people with Alzheimer's has identified five new risk genes, as well as confirmed 20 other known genes in the disease.... Read More...
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Never Before Seen DNA Recombination in Brain Linked to Alzheimer’s
Researchers identified gene recombination in neurons that produces new gene variants in the brains of those with Alzheimer's disease. The findings, researchers say, may point to a potential near term treatment for the neurodegenerative disease. ... Read More...
New Mechanism Involved in Age Related Memory Loss Discovered
Researchers report specific alterations in signaling circuits associated with memory can induce an abnormal response in neurons, which is linked to the aging process and cognitive decline. ... Read More...
Genes Linking Alzheimer’s to Down Syndrome Discovered
Researchers report extra copies of genes on chromosome 21 increase Alzheimer's like pathology and cognitive impairment in mouse models of Down syndrome. The findings provide insight into early onset Alzheimer's in those with Down syndrome.... Read More...
Viral Connection to Alzheimer’s: Herpes Virus Implicated in Alzheimer’s Disease
Researchers provide evidence that certain species of human herpesvirus contribute to the development of Alzheimer's disease. The study reports high levels of human herpesvirus 6A and 7 were found in brain samples showing signs of Alzheimer's neuropathology. The findings offer hints of the viral mechanisms that could trigger or exacerbate AD.... Read More...
Understanding the Origins of Alzheimer’s Disease
Researchers investigate the role the BMI1 gene plays in the onset and development of Alzheimer's disease. The study reports the loss of BMI1 triggers and increased production of amyloid beta and decreases neural ability to eliminate the protein.... Read More...
Epigenetic Balance Reinstates Memory in Fly Model of Alzheimer’s
A new study reports researchers have successfully reversed memory loss in fly models of Alzheimer's disease by restoring the balance between to enzymes that regulate gene expression.... Read More...
New Model Could Uncover Important Answers in Alzheimer’s Research
Researchers have developed a new rat model of Alzheimer's disease that can be used to study the accumulation of amyloid plaques.... Read More...
Researchers Successfully Reverse Alzheimer’s Disease: Mouse Study
Depleting BACE1 completely reverses the formation of amyloid plaques and improves cognitive function in mouse models of Alzheimer's disease, researchers report.... Read More...
Alzheimer’s Disease Might Be a ‘Whole Body’ Problem
Using a technique called parabiosis on pairs of mice, researchers discover what they call 'cancer like mobility' of amyloid beta, reporting it can travel to the brain from other parts of the body.... Read More...
One Step Closer Toward a Treatment for Alzheimer’s Disease?
Researchers have developed a new class of drugs that may be more precise at blocking the production of toxic forms of amyloid beta.... Read More...
Alzheimer’s Protein May Be Implicated in Children’s Cognitive Abilities
According to a new Journal of Alzheimer's Disease study, common genetic variants in amyloid precursor protein are associated with fluid intelligence in children.... Read More...