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This shows AB plaques surrounded by microglia

Featured Genetics Neurology Neuroscience

·April 16, 2021·5 min read

Some Alzheimer’s Plaques May Be Protective, Not Destructive

Microglia creates dense-core plaques which help to clear away more wispy plaques from neurons, preventing cell death. Findings suggest the dense-core plaques play a defensive role in protecting the brain from the ravages of neurodegenerative diseases, such as Alzheimer's. Read More

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·December 11, 2019·4 min read

Your genes aren’t the only factor dictating Alzheimer’s risk

While genetics may increase your risk of developing dementia, other factors such as lifestyle and environment may play a key role in the development and progression of Alzheimer's disease. Read More

Featured Neurology Neuroscience Open Neuroscience Articles

·September 27, 2019·8 min read

Common nutrient supplement choline may hold the answers to combating Alzheimer’s

Taking dietary choline supplements may help to protect the brain from Alzheimer's disease. Choline reduces the activation of microglia which, when overactivated, contribute to neuroinflammation and apoptosis associated with Alzheimer's. Choline also helps block the production of amyloid plaques. Read More

Featured Genetics Neurology Neuroscience

·August 23, 2019·6 min read

How ‘Australian’ mutation leads to Alzheimer’s disease

The 'Australian' familial genetic mutation, L723P, causes local unfolding of the C-terminal turn of the APP TM dominant helix. The findings suggest a mechanism of pathogenesis associated with the mutation. Read More

Featured Neurology Neuroscience Open Neuroscience Articles

·June 14, 2019·4 min read

Modified protein can prevent Alzheimer’s disease in mice

Researchers injected a modified segment of the amyloid precursor protein into mouse models of Alzheimer's disease. The treatment appeared to reverse a number of the cognitive and memory problems associated with the neurodegenerative disease. Read More

Featured Neurology Neuroscience

·May 28, 2019·6 min read

High LDL cholesterol linked to early-onset Alzheimer’s

Elevated levels of LDL cholesterol has been linked to an increased risk of early-onset Alzheimer's disease, in those with and without a genetic risk factor. This suggests cholesterol could be an independent risk factor for dementia. Additionally, researchers identified a potential new genetic risk factor for early-onset Alzheimer's, a rare variant of the APOB gene. Read More

Featured Neurology Neuroscience

·April 23, 2019·4 min read

Scientists propose new theory on Alzheimer’s, amyloid connection

Study finds a 'peculiar association' between amyloid precursor protein and cholesterol in the cell membrane of synapses. Amyloid precursor protein may contribute to cholesterol deficiency, triggering neurodegeneration in Alzheimer's disease. Read More

Featured Genetics Neurology

·February 28, 2019·5 min read

Data Sharing Uncovers Five New Risk Genes For Alzheimer’s

A new study of the genetic data from over 94,000 people with Alzheimer's has identified five new risk genes, as well as confirmed 20 other known genes in the disease. Read More

Featured Genetics Neurology

·November 26, 2018·6 min read

Never Before Seen DNA Recombination in Brain Linked to Alzheimer’s

Researchers identified gene recombination in neurons that produces new gene variants in the brains of those with Alzheimer's disease. The findings, researchers say, may point to a potential near term treatment for the neurodegenerative disease. Read More

Featured Neuroscience Open Neuroscience Articles

·June 27, 2018·4 min read

New Mechanism Involved in Age Related Memory Loss Discovered

Researchers report specific alterations in signaling circuits associated with memory can induce an abnormal response in neurons, which is linked to the aging process and cognitive decline. Read More

Featured Genetics Neurology Psychology

·June 26, 2018·5 min read

Genes Linking Alzheimer’s to Down Syndrome Discovered

Researchers report extra copies of genes on chromosome 21 increase Alzheimer's like pathology and cognitive impairment in mouse models of Down syndrome. The findings provide insight into early onset Alzheimer's in those with Down syndrome. Read More

a brain with a drawing of a viral vector on top

Artificial Intelligence Deep Learning Featured Genetics Neurology Neurotech Open Neuroscience Articles

·June 21, 2018·10 min read

Viral Connection to Alzheimer’s: Herpes Virus Implicated in Alzheimer’s Disease

Researchers provide evidence that certain species of human herpesvirus contribute to the development of Alzheimer's disease. The study reports high levels of human herpesvirus 6A and 7 were found in brain samples showing signs of Alzheimer's neuropathology. The findings offer hints of the viral mechanisms that could trigger or exacerbate AD. Read More

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