Researchers report extra copies of genes on chromosome 21 increase Alzheimer's like pathology and cognitive impairment in mouse models of Down syndrome. The findings provide insight into early onset Alzheimer's in those with Down syndrome.
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Researchers provide evidence that certain species of human herpesvirus contribute to the development of Alzheimer's disease. The study reports high levels of human herpesvirus 6A and 7 were found in brain samples showing signs of Alzheimer's neuropathology. The findings offer hints of the viral mechanisms that could trigger or exacerbate AD.
Researchers investigate the role the BMI1 gene plays in the onset and development of Alzheimer's disease. The study reports the loss of BMI1 triggers and increased production of amyloid beta and decreases neural ability to eliminate the protein.
A new study reports researchers have successfully reversed memory loss in fly models of Alzheimer's disease by restoring the balance between to enzymes that regulate gene expression.
Researchers have developed a new rat model of Alzheimer's disease that can be used to study the accumulation of amyloid plaques.
Depleting BACE1 completely reverses the formation of amyloid plaques and improves cognitive function in mouse models of Alzheimer's disease, researchers report.
Using a technique called parabiosis on pairs of mice, researchers discover what they call 'cancer like mobility' of amyloid beta, reporting it can travel to the brain from other parts of the body.
According to a new Journal of Alzheimer's Disease study, common genetic variants in amyloid precursor protein are associated with fluid intelligence in children.
Researchers at UBC believe they have identified a method that could help stop Alzheimer's disease in its tracks.
A new drug has proven effective at restoring memories and neural connections in mouse models of Alzheimer's disease. The new drug was originally developed as a treatment for Schizophrenia. While the drug does not destroy amyloid plaques associated with Alzheimer's, it does allow the plaques to co-exist with neurons.
Study offers insight into the link between the immune system and the development of Alzheimer's disease.