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APP

·December 16, 2016·7 min read

A Link Between HIV Treatment and Neurodegeneration

Researchers discovered some protease inhibitors used to treat HIV can lead to the production of the peptide amyloid beta.

Featured Neurology

·October 4, 2012·3 min read

A Molecular Scissor Related to Alzheimer’s Disease

An international research team revealed the atomic‐level structure of the human peptidase enzyme meprin β (beta).

Featured Neurology

·November 2, 2015·3 min read

A New Link Between Alzheimer’s Disease and Down Syndrome

A new study reports the dementia associated with Down syndrome involves defects in GSAP, which also malfunctions in Alzheimer's disease.

Image shows a a diagram of a mouse and the continental US.

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·January 31, 2017·7 min read

Air Pollution May Lead to Dementia in Older Women

Researchers report older women living in areas with fine particulate matter exceeding the EPA's standard are at significantly higher risk of developing dementia.

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·May 19, 2021·4 min read

Alzheimer Protein App Regulates Learning and Social Behavior in the Healthy Brain

APP, a protein commonly associated with Alzheimer's disease, plays a vital role in learning, memory, and social behavior in the developing brain, a new mouse study finds.

Featured Neurology

·October 31, 2017·4 min read

Alzheimer’s Disease Might Be a ‘Whole Body’ Problem

Using a technique called parabiosis on pairs of mice, researchers discover what they call 'cancer like mobility' of amyloid beta, reporting it can travel to the brain from other parts of the body.

The image shows BACE1 and APP in the alzheimer's brain slices. The caption best describes the image.

Featured Genetics Neurology Open Neuroscience Articles

·January 15, 2015·5 min read

Alzheimer’s Plaques Reduced by Targeting Sugar Attachment to the BACE1 Enzyme

Amyloid beta can be reduced when sugars are prevented from binding to a key enzyme associated with Alzheimer's disease, researchers report.

Featured Genetics Neurology Neuroscience

·June 17, 2026·9 min read

Alzheimer’s Protein APP Acts as Vital Shield for Neurons

A new study reveals that amyloid precursor protein (APP), long studied merely as the source of toxic plaques in Alzheimer's disease, serves a vital protective role as a cellular guardian.

Featured Genetics Neurology Open Neuroscience Articles

·August 2, 2017·4 min read

Alzheimer’s Protein May Be Implicated in Children’s Cognitive Abilities

According to a new Journal of Alzheimer's Disease study, common genetic variants in amyloid precursor protein are associated with fluid intelligence in children.