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antidepressants

·August 21, 2021·5 min read

Neuroactive Steroids May Induce Prolonged Antidepressant Effects by Altering Brain States

Allopregnanolone, a neuroactive steroid used in the treatment of postpartum depression, alters neural communication in the basolateral amygdala, an area of the brain associated with emotion and mood regulation. The drug may alter the network associated with chronic stress, which may explain its persistent antidepressant effect.

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·August 17, 2021·4 min read

Histamine and Inflammation Could Be Key Players in Depression

A new study adds to the growing body of research linking inflammation to depression. Researchers found the molecule histamine directly inhibits the release of serotonin in the brain by attaching to inhibitory receptors on serotonin neurons in mice.

Featured Genetics Neuroscience Psychology

·July 28, 2021·3 min read

Discovery Points to Ketamine’s Long-Term Antidepressant Effects

The MeCP2 gene influences ketamine's behavioral effect and strengthens synapses, leading to an improvement in the drug's antidepressant effect over time.

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·June 24, 2021·4 min read

Antidepressants Safe During Pregnancy

Taking SSRI antidepressants does not increase the risk of developmental delays or autism in children, a new study reports. However, there is an increased risk for ASD and developmental delays in children whose mothers suffer from maternal psychiatric disorders.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·June 1, 2021·6 min read

Protecting the Intellectual Abilities of People at Risk for Psychosis

Prescribing SSRIs during late childhood to those with genetic risk factors for psychosis can reduce the deterioration of intellectual abilities, a new study reveals. SSRIs appear to have a neuroprotective effect for certain brain areas associated with the onset of psychosis if provided early.

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Featured Neuroscience Psychology

·May 28, 2021·4 min read

Why Is It so Hard to Withdraw From Some Antidepressants?

A new study reveals the molecular and cellular mechanisms behind why some people find it harder to stop using antidepressants than others with depression.

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Featured Neuroscience Psychology

·April 16, 2021·8 min read

Psilocybin Performs At Least As Well as Leading Antidepressant in Small Study

Psilocybin, the psychoactive compound found in magic mushrooms, is as effective at treating depression as conventional SSRI antidepressants. Researchers report, that although not significantly significant, early findings reveal those treated with psilocybin experienced more rapid and greater reductions in depression symptoms than those treated with SSRIs.

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Featured Neuroscience Psychology

·April 13, 2021·4 min read

Psychedelic Experience May Not Be Required For Psilocybin’s Antidepressant-Like Benefits

A mouse study refutes the common belief that psilocybin's ability to produce an anti-depressant effect is attributed to the psychedelic experience it creates. Blocking the psychedelic effect did not affect psilocybin's anti-depressant effects.

This shows a depressed looking young man

Featured Neuroscience Psychology

·February 18, 2021·4 min read

New Information on the Effects of Antidepressants

SSRI's, ketamine, and tricyclic antidepressants all bind with TrkB. The findings challenge the roles serotonin and glutamate receptors play in the effects of antidepressant medications.

Featured Genetics Neuroscience Psychology

·January 5, 2021·5 min read

New Clues Why Gold Standard Treatment for Bipolar Disorder Doesn’t Work for Majority of Patients

Decreased activation of the LEF1 gene is more common in bipolar patients who do not respond to lithium.

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·December 28, 2020·4 min read

New Antidepressants Can Lift Depression and Suicidal Thoughts Fast, but Don’t Expect Magic Cures

With the risk of potential for abuse, some new fast-acting antidepressants, like Ketamine, may not be a magic "cure-all" for depression.

Featured Neuroscience Open Neuroscience Articles Psychology

·November 13, 2020·6 min read

Antidepressant May Prevent Severe COVID-19, Trial Suggests

A new small scale study reveals the antidepressant fluvoxamine may be a new tool in the fight against COVID-19. Researchers report fluvoxamine reduced the severity of coronavirus symptoms and hospitalizations.