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antidepressants

·March 6, 2022·3 min read

Pregnant Women Have Lingering Depression Despite Antidepressant Treatment

Many women experienced lingering depression throughout pregnancy and postpartum, despite using SSRI antidepressants, a new study reports.

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·January 3, 2022·4 min read

Researchers Identify Biomarker for Depression and Antidepressant Response

Researchers have identified a novel biomarker for depression and antidepressant response. The biomarker can be identified and monitored through blood samples.

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·December 5, 2021·4 min read

New Insight Into How Antidepressant Drugs Work

Hippocampal HCN channels are more highly expressed in people with major depressive disorder. Antidepressants that increase cAMP signaling interfere with TRIP8b's ability to bind to HCN channels, helping to restore cognitive ability in those with MDD.

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·November 27, 2021·5 min read

Looking to Mitochondria for Clues About Depression

People with untreated depression have lower levels of mitochondrial proteins. For those who responded to the SSRI antidepressants, the proteins returned to a normal level, but showed no increase in those who did not respond to medication.

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·November 15, 2021·4 min read

COVID Patients on SSRI Antidepressants Are Less Likely to Die

A comparison of medical records reveals people who took SSRI antidepressants, specifically fluoxetine (Prozac), were less likely to die of COVID-19 than a matched control group. The findings add to a growing body of evidence that SSRIs may have beneficial effects against the worst symptoms of coronavirus.

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·November 12, 2021·3 min read

New Target Identified for Rapid Antidepressant Drugs

Ketamine's rapid antidepressant action is due to specific synaptic effects, researchers report.

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·November 9, 2021·5 min read

New Imaging Biomarkers That Predict Antidepressant Response Identified

Combining neuroimaging and artificial intelligence, researchers identified novel brain signatures unique to the response of each antidepressant.

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·November 8, 2021·4 min read

Expectations and Dopamine Can Affect Outcome of SSRI Antidepressant Treatment

The placebo effect combined with dopamine levels can determine whether symptoms of depression and social anxiety will improve in patients prescribed SSRI antidepressants. Researchers found the positive effect of the medications was four times higher in patients with high expectations the treatment would work compared to those with lower expectations.

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·October 22, 2021·4 min read

Common Antidepressant Should No Longer Be Used to Treat People With Dementia

Mirtazapine, an antidepressant commonly prescribed to treat dementia-associated agitation, is no more effective than a placebo and may increase mortality risks, researchers report.

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·October 5, 2021·4 min read

Psilocybin Affects Perception of Music

Psilocybin, a natural psychoactive compound currently being considered for the treatment of depression, alters people's emotional states while listening to music. While listening to music, those who used psilocybin reported enhanced emotional processing. Researchers say combining music with psychedelic therapy may have positive benefits for those suffering from depression.

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·August 30, 2021·3 min read

Brain Cells Conduct Antidepressant Action Even in the Absence of Activity

In the absence of neural activity, BDNF expression can still be activated. The findings shed light on how therapeutic ketamine used has an antidepressant effect and how it works in both the long and short term.