amyotrophic lateral sclerosis

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amyotrophic lateral sclerosis

Featured Genetics Neurology Neuroscience

·April 20, 2020

Researchers delay onset of ALS

Increasing the activity of interneurons in later 5 of the primary motor cortex in mouse models of ALS effectively slowed the onset of the disease. Read More

Featured Genetics Neurology Neuroscience

·March 27, 2020

Gene that first slows, then accelerates, progression of ALS in mice identified

The TBK1 gene regulates the disease progression of ALS in mouse models of the neurodegenerative disease. Loss of the TBK1 gene in motor neurons increases SOD1 aggregation and accelerates the onset of the disease. Read More

Featured Genetics Neurology Neuroscience

·February 11, 2020

Speeding up treatments for ALS

Study reports protein aggregates within cells are cleared out by the endocytosis process. The findings could help with the development of new treatments for ALS. Read More

Electrophysiology Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·January 12, 2020

Neurons’ energy organelle protected from damage linked to ALS & Alzheimer’s

Researchers have identified a set of drug-like compounds, including a common ingredient in throat lozenges, that can help protect mitochondria from the stresses associated with neurodegenerative diseases. Read More

This shows a turtle's spinal cord neurons

Featured Neuroscience Open Neuroscience Articles

·September 19, 2019

Neurological signals from the spinal cord surprise scientists

A new study challenges existing theories about spinal cord neurons. New findings suggest neurological signals originate from a major, scattered network of cells that send signals to only a few other neurons. Read More

Featured Neurology Neuroscience Open Neuroscience Articles

·September 17, 2019

Environmental toxin produced by algae may lead to ALS

Exposure to the environmental toxin BMAA may elevate the risk of ALS. BMAA is produced by cyanobacteria, a blue-green alga that commonly occurs in marine ecosystems and accumulates in shellfish, sharks, and other sea-life. Those most reliant on sea-foods for their food source may be most at risk. Read More

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·September 4, 2019

New insight into motor neuron death mechanisms could be a step toward ALS treatment

When a motor neuron-specific pool of heat shock protein 90 (Hps90) was inhibited, motor neuron apoptosis was triggered. Read More

Featured Neurology Neuroscience

·July 22, 2019

Gut microbes may affect the course of ALS

Researchers have isolated a molecule that may be under-produced in the gut of those with ALS. Using mouse models of the disease, researchers identified 11 microbial strains that became altered as the disease progressed, or before the development of symptoms. Read More

Featured Genetics Neurology Neuroscience Open Neuroscience Articles Psychology

·July 11, 2019

Are the ‘viral’ agents of MS, ALS and schizophrenia buried in our genome?

Retroviruses may be a missing causal link in diseases like ALS, multiple sclerosis and schizophrenia. Read More

This shows two head outlines with drawings of brains in them

Featured Genetics Neurology Neuroscience

·July 6, 2019

To cure brain diseases, neuroscientists must collaborate: That’s why I’m giving my data away

Open sharing of scientific data and standard methods will allow researchers to collaborate on projects and accelerate understanding of neurodegenerative diseases. Read More

Featured Neurology Neuroscience

·July 2, 2019

Copper compound shows further potential as therapy for slowing ALS

Treatment with copper-ATSM helped mouse models retain behavioral performance and prevented extensive motor neuron degeneration and microglial activation associated with ALS. Read More

Featured Neurology Neuroscience

·June 27, 2019

Weight gain and high BMI linked to lower risk of ALS

While being overweight may be bad for your general health, researchers discovered an association with higher body mass index (BMI) and a reduced risk of developing ALS. Those with a BMI considered to be in the obese range had a 31% reduced risk of developing ALS, while those considered overweight had an 18% lower risk. Read More

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