Latest

amyotrophic lateral sclerosis

Featured Neurology Neuroscience Open Neuroscience Articles

·January 28, 2022·4 min read

Simple and Reliable ALS Diagnosis With Blood Tests

Measuring the level of neurofilaments in the blood may be a reliable biomarker for the early diagnosis of ALS.

Featured Genetics Neurology Neuroscience

·January 19, 2022·6 min read

Astrocyte Studies Reveal Harmful Changes in Amyotrophic Lateral Sclerosis

In patients with ALS, astrocytes within the brain become pro-inflammatory and tend to lose their protective function, resulting in changes in the ability to uptake glutamate.

Featured Neurology Neuroscience

·November 10, 2021·4 min read

New Insights on ALS May Point To a Potentially Promising Treatment Strategy

Post-mortem studies of brain tissue from ALS patients reveal an abnormal form of tau is present in novel brain areas, and the tau interacts with DRP1. The tau appears to cause the brain cell's mitochondria to fragment and increase oxidative stress. Reducing tau reversed the effect, decreasing oxidative stress and mitochondrial fragmentation.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·August 6, 2021·5 min read

Key Hallmark of ALS Reversed

Researchers reveal how proteins accumulate in the incorrect parts of brain cells in ALS, and demonstrate how it may be possible to reverse the accumulation.

Featured Genetics Neurology Neuroscience

·July 8, 2021·4 min read

ALS: Study Shows Role of Brain’s Immune Cells

Hyperactive microglia immune cells may play a significant role in the development of ALS, researchers report.

This shows a woman, a brain and a neuron

Featured Neurology Neuroscience

·February 23, 2021·5 min read

ALS Neuron Damage Reversed With New Compound

NU-9, a novel, non-toxic compound, targets upper motor neurons and reverses damage associated with ALS within 60 days of treatment.

Featured Genetics Neurology Neuroscience

·December 9, 2020·4 min read

New Biomarker Candidate for ALS

A novel method detected conformational changes to the TDP-43 protein in cerebral spinal fluid associated with ALS.

Featured Neurology Neuroscience Open Neuroscience Articles

·September 8, 2020·5 min read

Investigational Drug Stops Toxic Proteins Tied To ALS

c9ASO, an investigational ASO drug, targets the TDP-43 protein, reducing its buildup and decreasing neurological decline associated with ALS and FTD.

Featured Neurology Open Neuroscience Articles

·September 3, 2020·4 min read

Promising New ALS Drug Candidates

Ebselen, a Selenium-based drug molecule, and several other novel compounds can change the characteristics of SOD1. The findings could help with the development of new therapeutics for ALS.

Featured Genetics Neurology Neuroscience

·April 20, 2020·5 min read

Researchers delay onset of ALS

Increasing the activity of interneurons in later 5 of the primary motor cortex in mouse models of ALS effectively slowed the onset of the disease.

Featured Genetics Neurology Neuroscience

·March 27, 2020·6 min read

Gene that first slows, then accelerates, progression of ALS in mice identified

The TBK1 gene regulates the disease progression of ALS in mouse models of the neurodegenerative disease. Loss of the TBK1 gene in motor neurons increases SOD1 aggregation and accelerates the onset of the disease.

Featured Genetics Neurology Neuroscience

·February 11, 2020·4 min read

Speeding up treatments for ALS

Study reports protein aggregates within cells are cleared out by the endocytosis process. The findings could help with the development of new treatments for ALS.

1 2 3 4 5 … 16

amyotrophic lateral sclerosis

Simple and Reliable ALS Diagnosis With Blood Tests

Astrocyte Studies Reveal Harmful Changes in Amyotrophic Lateral Sclerosis

New Insights on ALS May Point To a Potentially Promising Treatment Strategy

Key Hallmark of ALS Reversed

ALS: Study Shows Role of Brain’s Immune Cells

ALS Neuron Damage Reversed With New Compound

New Biomarker Candidate for ALS

Investigational Drug Stops Toxic Proteins Tied To ALS

Promising New ALS Drug Candidates

Researchers delay onset of ALS

Gene that first slows, then accelerates, progression of ALS in mice identified

Speeding up treatments for ALS

How Scientists Cracked the Ketamine Code for Depression

Brain Prioritizes “Sound Offsets” During Hearing Repair

Glucose Levels Signal the Growth of Myelin

Why Your Brain “Dreams” Even When You’re Awake

Subscribe