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Alzheimer’s disease

Featured Genetics Neurology Neuroscience

·April 6, 2020·4 min read

Alzheimer’s trial screening data links high amyloid levels with early stage disease

Findings support the hypothesis that higher levels of amyloid in the brain is an indicator of the early stages of Alzheimer's disease.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·April 1, 2020·3 min read

Scientists discover gene that increases risk of Alzheimer’s disease

The ECE2 gene has been linked to an increased risk of developing late-onset Alzheimer's disease.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 31, 2020·3 min read

Amyloid formation drives brain tissue loss

Animal study reveals the formation of amyloid plaques drives brain tissue loss and neurodegeneration in Alzheimer's disease. However, lithium, a drug commonly used to treat bipolar disorder, reduces the life-shortening effects of the loss.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 31, 2020·4 min read

Discovery of new biomarker in blood could lead to early test for Alzheimer’s disease

Increased levels of PHGDH exRNA levels were found in the blood approximately two years before people were clinically diagnosed with Alzheimer's disease.

Featured Neurology Neuroscience

·March 25, 2020·3 min read

Early-life hardship linked to decline in memory and thinking

Experiencing adversity in childhood could influence cognitive performance in older age. Adults who had fewer years of education, economic hardships, and poor health during childhood were more likely to experience cognitive decline and memory problems later in life.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·March 18, 2020·5 min read

Alzheimer’s risk genes converge on microglia

Findings indicate a large part of the genetic risk of Alzheimer's involves a microglial response to amyloid-beta.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 17, 2020·5 min read

Inflammation in the brain linked to several forms of dementia

In all three types of frontotemporal dementia, researchers found the more the inflammation in each part of the brain, the more harmful the build-up of junk proteins.

Featured Neuroscience

·March 16, 2020·4 min read

New research on brain structure highlights cells linked to Alzheimer’s and autism

Astrocytes are not uniform, as previously believed, but take distinct molecular forms depending on their location in the cerebral cortex. Astrocytes also organize in layers in similar ways to neurons.

This shows an older person and a young person on a hammock

Featured Neurology Neuroscience Psychology

·March 12, 2020·5 min read

Personality traits found to be protective in Alzheimer’s disease

Your personality traits might indicate whether you are at an increased risk of developing Alzheimer's disease as you age. Those who are less agreeable and more confrontational appear to have better neuroprotection against the disease. Lower agreeableness was associated with lower brain volume loss in the hippocampus, entorhinal cortex, and other areas linked to memory. Higher openness was also associated with lower brain volume loss in the hippocampus. The data suggests a combination of lower agreeableness and higher openness could be independent predictors of the preservation of brain volume in areas vulnerable to neurodegeneration.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 11, 2020·4 min read

Common muscle relaxant given via nose shows potential to treat Alzheimer’s

Dantrolene, a common muscle relaxant, shows promise in the treatment of Alzheimer's disease. Mice administered the drug intranasally had higher concentrations of the medicine in their brains, and for longer periods, than those who received it orally. The drug has been shown to help inhibit or slow the progression of several neurodegenerative diseases.

This shows microglia, neurons and plaques

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·March 10, 2020·4 min read

Stimulating immune cells to protect against Alzheimer’s

Stimulating activation of microglia may help eliminate Alzheimer's associated plaques, thus helping to prevent the progression of the neurodegenerative disease.

Autism Featured Genetics Neuroscience

·March 2, 2020·4 min read

Could targeting an Alzheimer’s-associated protein prevent Autism?

Reducing levels of the Alzheimer's related Tau protein prevents autism-like behaviors in mouse models. Tau reduction also prevented seizures in the animals.

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Alzheimer’s disease

Alzheimer’s trial screening data links high amyloid levels with early stage disease

Scientists discover gene that increases risk of Alzheimer’s disease

Amyloid formation drives brain tissue loss

Discovery of new biomarker in blood could lead to early test for Alzheimer’s disease

Early-life hardship linked to decline in memory and thinking

Alzheimer’s risk genes converge on microglia

Inflammation in the brain linked to several forms of dementia

New research on brain structure highlights cells linked to Alzheimer’s and autism

Personality traits found to be protective in Alzheimer’s disease

Common muscle relaxant given via nose shows potential to treat Alzheimer’s

Stimulating immune cells to protect against Alzheimer’s

Could targeting an Alzheimer’s-associated protein prevent Autism?

Decreasing Productivity Can Precede a Dementia Diagnosis by Years

Study Maps the 9 Distinct Types of Procrastinators

AI Chip Mimicking Brain’s Reflex Center Developed

Study Overturns Decades of External Axon Growth Theory

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