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Alzheimer’s disease

This photo shows two lab mice in a researcher's hand.

·July 16, 2013·5 min read

Potential Neurological Treatments Often Advance to Clinical Trials on Shaky Evidence

A new study claims clinical trials for neurological diseases often fail because the animal studies which preceded them were poorly designed or biased in their interpretation.

The brain diagram highlights the temporal lobe in yellow.

Featured Neurology

·July 15, 2013·4 min read

Path of Plaque Buildup in Brain Shows Promise as Early Biomarker for Alzheimer’s Disease

Researchers discover early accumulation of amyloid plaques in the temporal lobe is associated with cognitive decline. The finding could serve as a new biomarker for the early detection of Alzheimer's disease.

The image shows prefoldin protein expression in mice.

Featured Neurology

·July 12, 2013·2 min read

Fighting Alzheimer’s Disease with Protein Origami

Researchers find the human protein prefoldin can reduce neurotoxicity in the clumps of beta-amyloid which collects in the brains of Alzheimer's patients.

The image shows PET brain scans of a normal brain, one affected by mild cognitive impairment and one with alzheimer's.

Featured Neurology

·July 10, 2013·4 min read

Women Suffer Higher Rates of Cognitive Decline in Alzheimer’s Disease

A new study suggests the rate of regional brain loss and cognitive decline caused by early stages of Alzheimer's disease is higher in women and those with a genetic risk factor for AD.

This image shows the brain of an older man, along with an image of an elderly male.

Featured Neurology

·July 8, 2013·1 min read

Researchers Investigate Mechanism of Alzheimer’s Therapy

A new study suggest IVIg plays a key role in the reduction of amyloid deposition.

Three panels show tangles and Lewy bodies.

Featured Neurology

·July 3, 2013·4 min read

Shape-shifting Disease Proteins May Explain Variable Appearance of Neurodegenerative Diseases

Researchers discover alpha-synuclein proteins can morph into different strains. This can promote misfolding of other disease proteins associated with neurodegenerative diseases.

The image shows the DAF-2 mutants with decreased insulin/IGF-1 signalling. The caption best describes the image.

Featured Neurology Open Neuroscience Articles

·July 1, 2013·2 min read

Researchers Have Discovered a New Proteasome Regulatory Mechanism

A new study uncovers a new proteasome regulatory mechanism which could bear significance in the treatment of neurodegenerative diseases and some cancers.

This image shows amyloid beta plaques associated with Alzheimer's disease.

Featured Neurology

·July 1, 2013·4 min read

Lack of Immune Cell Receptor Impairs Clearance of Amyloid Beta Protein from the Brain

Researchers discover increased expression of the Scara1 protein could impede the progression of Alzheimer's disease as it plays an important role in the removal of amyloid beta from the brain.

The illustration is a brain slice with advanced stage alzheimer's.

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·June 28, 2013·5 min read

Scientists View ‘Protein Origami’ to Help Understand, Prevent Certain Diseases

Using sophisticated imaging techniques, researchers observe a molecular protein folding process which could help better understand and treat neurodegenerative diseases and cancers.

This illustration compares a normal brain to an alzheimer's brain.

Featured Neuroscience

·June 28, 2013·3 min read

Identifying Alzheimer’s Using Space Technology

According to the ESA, software which processes satellite pictures taken from space is helping researchers establish a simple method for wide-scale Alheimer's screening.