Neuroscience NewsSummary: Drinking small amounts of alcohol, like one pint of beer or a large glass of wine, significantly impairs our feeling of being in control of our actions. A new study reveals even one beer can lead to overconfidence in driving ability and make us act in inappropriate, potentially dangerous ways. The study begs the question, are current alcohol limits for driving truly safe?
Source: University of Sussex
New research by neuroscientists from the University of Sussex shows that drinking only one pint of beer or large glass of wine is enough to significantly compromise a person’s sense of agency.
Sense of agency is the feeling of being in control of our actions. It is an important aspect of human social behaviour, as it implies knowledge of the consequences of those actions.
This new study, Effect of alcohol on the sense of agency in healthy humans, is the first to test the effect of alcohol on the sense of agency. The study focused on low doses of alcohol, typically consumed during social drinking, that do not produce a large impairment of behaviour. Until now, research has mostly focused on the loss of inhibitory control produced by obvious drunkenness, characterised by impulsivity, aggression, and risky behaviour.
Dr Silvana De Pirro, lead author of the research paper, said: “Our study presents a compelling case that even one pint of beer is enough to significantly compromise a person’s sense of agency. This has important implications for legal and social responsibility of drivers, and begs the question: are current alcohol limits for driving truly safe?”
Explaining how the study was conducted, Dr De Pirro said: “Measuring a person’s sense of agency is tricky. When people are explicitly asked to tell how in control they feel, their answers are affected by several cognitive biases, such as poor introspection, the desire to conform to researchers’ expectations, or even the inability to understand the question correctly.”
Sussex researchers relied therefore on an indirect measure called ‘intentional binding’, which has been developed to investigate the unconscious mechanisms of ‘volition’. When physical stimuli (such as sounds or lights) follow voluntary actions (such as moving a finger or a hand), people judge actions as occurring later and stimuli as occurring earlier than in reality, hence ‘binding’ the two. The neural mechanisms responsible for this phenomenon are thought to participate in creating the sense of agency.
Even one pint of beer can compromise driving safety The image in the public domain.
In the experiments, subjects drank a cocktail containing doses of alcohol proportional to their BMI to produce blood alcohol concentrations within the legal limits for driving in England and Wales. These doses of alcohol, corresponding to one or two pints of beer, produced tighter binding between voluntary actions and sensory stimuli. This suggests that small amounts of alcohol might exaggerate the sense of agency, leading to overconfidence in one’s driving ability and to inappropriate, potentially dangerous behaviour.
Professor Aldo Badiani, Director of the Sussex Addiction Research and Intervention Centre (SARIC), said: “It’s important to note that in our experiments, all the participants stayed within the legal alcohol limit for driving in England, Wales, the US and Canada. And yet we still saw an impairment in their feeling of being in control.
“In England, Wales and North-America, the argument to lower the limit has much momentum. The results of our study support the implementation of such a change in the law.”
The legal limit for driving in England and Wales is currently 80 mg/100 ml. The legal limit for driving in Scotland and most European countries is 50 mg/100 ml.
The study, Effect of alcohol on the sense of agency in healthy human, published in Addiction Biology today Friday 21 June, was the result of a collaboration of the Sussex Addiction Research and Intervention Centre, Sussex Neuroscience and the Sackler Centre for Consciousness Science at the University of Sussex, with the Department of Physiology and Pharmacology at the Sapienza University of Rome, Italy.
Source:
University of Sussex
Media Contacts:
Anna Ford – University of Sussex
Image Source:
The image is in the public domain.
Original Research: Closed access
“Effect of alcohol on the sense of agency in healthy humans”. Silvana De Pirro, Peter Lush, Jim Parkinson, Theodora Duka, Hugo D. Critchley, Aldo Badiani.
Addiction Biology. doi:10.1111/adb.12796
Abstract
Effect of alcohol on the sense of agency in healthy humans
Even at low to moderate doses, ingestion of the widely used recreational drug alcohol (ethanol) can impact cognitive and emotional processing. Recent studies show that the sense of agency (SoA; ie, the subjective experience of voluntary control over actions) can be modulated by specific pharmacological manipulations. The SoA, as quantified by the intentional binding (IB) paradigm, is enhanced by direct or indirect dopaminergic agonists in patients with Parkinson’s disease and by ketamine (an N‐methyl‐D‐aspartate (NMDA) receptor antagonist) in healthy individuals. These findings implicate dopaminergic and glutamatergic neurotransmission in mechanisms underlying SoA. Alcohol has a complex set of actions, including disinhibition of dopaminergic neurotransmission and allosteric antagonism at NMDA receptors. Here, we tested the hypothesis that low to moderate doses of alcohol would enhance SoA, and impact impulsivity and subjective emotional state. We conducted two experiments in 59 healthy male and female social drinkers, who ingested either a placebo “vehicle,” or one of two doses of ethanol: 0.4 and 0.6 g/kg. In both experiments, we observed increased SoA/IB at both doses of alcohol exposure, relative to the placebo condition. We found no correlation between the effects of alcohol on IB and on impulsivity or subjective emotional state. Our findings might have implications for social and legal responsibility related to alcohol use, particularly in states prior to overt intoxication. Further studies are necessary to investigate the effects of alcohol and other addictive substances on the SoA.