alcohol use disorder

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alcohol use disorder

·March 6, 2023·5 min read

How Heavy Alcohol Consumption Increases Brain Inflammation

The immune signaling molecule interleukin 1B (IL-1B) is present at higher levels in mouse models of alcohol use disorder. The IL 1B pathway plays a different role in animal models of AUD, causing inflammation in brain areas that play a critical role in decision-making.

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·February 21, 2023·5 min read

Medication Targeting Brain Stress Response May Help Cardiovascular Symptoms of Alcohol Withdrawal

Prazosin, an FDA-approved medication for the treatment of hypertension may help to prevent relapse in people with cardiovascular and behavioral symptoms of alcohol withdrawal, a new study reports.

Featured Neuroscience Psychology

·February 21, 2023·4 min read

Pill for Skin Disease Also Curbs Excessive Drinking

Apremilast, an FDA-approved drug for the treatment of skin conditions including psoriasis and psoriatic arthritis, triggers increased activity in the nucleus accumbens, a brain area associated with regulating alcohol intake. Apremilast reduced drinking behaviors in mouse models with a genetic risk of alcohol use disorder.

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·February 7, 2023·5 min read

Differences in Dopamine Signals in Patients With History of Alcohol Use Disorder

The connection between dopamine and counterfactual information, or notions of relief and regret, is altered in those with alcohol use disorder.

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·January 31, 2023·4 min read

Mocktails or Cocktails? Having a Sense of Purpose in Life Can Keep Binge Drinking at Bay

Having a sense of purpose in life decreases alcohol consumption and binge drinking temptation in some social drinkers.

Featured Neuroscience Psychology

·January 30, 2023·4 min read

Experimental Anti-depression Drug May Also Be Useful in Treating Alcohol Use Disorder

MAP4343, an experimental antidepressant compound reversed alcohol intake in rat models of alcohol use disorder. The findings pave the way for utilizing the compound for the treatment of AUD in humans.

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·January 21, 2023·5 min read

Close Relationships With Parents Promote Healthier Brain Development in High-Risk Teens, Buffering Against Alcohol Use Disorder

Close and supportive parental relationships can help mitigate the genetic and environmental risk of developing alcohol use disorder for at-risk teens.

This shows a young person drinking at the side of a road

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·January 19, 2023·4 min read

Heavy Drinking in Young Adults Tied to Endocannabinoid Pathway

Brain levels of FAAH, an enzyme that degrades a neurotransmitter that activates the cannabinoid 1 receptor, may contribute to the maintenance of excessive drinking and susceptibility to alcohol use disorder.

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·December 16, 2022·4 min read

Fathers Who Drink Heavily Report Less Positive Involvement With Their Children

Fathers who binge drink are less involved with their children, a new study reports. Treating paternal heavy alcohol use can improve family dynamics.

This is a drawing of a young woman smoking a pipe

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·December 5, 2022·3 min read

Young People Are Ditching Alcohol for Marijuana

Since 2000, marijuana use in young adults has increased by 245%, while alcohol use in adolescents has seen a steady decline.

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·November 18, 2022·5 min read

Can Pharmacotherapies Prevent Alcohol Use Disorder in People With PTSD?

Those with PTSD are almost twice as likely to develop alcohol use disorder than their peers who have not experienced trauma. Researchers report drugs that block FKBP5, such as benztropine, a drug used to control symptoms of Parkinson's disease, and the experimental compound SAFit2 reduce alcohol preference and drinking in models of PTSD.

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·September 20, 2022·5 min read

Heart Medication Shows Potential as Treatment for Alcohol Use Disorder

Spironolactone, a medication commonly used to lower blood pressure and for treating heart-related problems, shows potential for the treatment of alcohol use disorder.

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