Researchers have identified 579 genetic loci associated with increased risk of disorders associated with self-regulation disorders including addiction, ADHD, and anti-social behavior.
Men who are intoxicated with alcohol have impairments when it comes to correctly assessing emotional facial cues in others. Researchers speculate the findings may explain why alcohol use is often associated with harmful interpersonal and social interactions, such as aggression and domestic violence.
A new dual-drug therapy for alcohol use disorder appears to be effective and has fewer side effects or complications compared to other medications used to treat AUD.
Blocking hippocampal STAT3 in those with alcohol use disorder may alleviate symptoms of depression associated with withdrawal.
A new study reveals sex differences in the way those with alcohol use disorder process facial emotions. Men with AUD showed greater activation in frontal brain areas when processing facial emotions. The increased activation was not seen in women with AUD.
A new series of studies review the roles neuroplasticity and neurogenesis play in alcohol addiction and recovery.
Researchers have identified a pathway in the brain responsible for the development of alcohol addiction.
People who are most sensitive to the pleasurable and rewarding effects of alcohol are at greater risk of developing alcohol use disorders.
Manipulating memory via optogenetics mitigated addiction-related behaviors.
Low-level exposure to lead during development does not lead to alcohol use disorder, but does alter the neural circuits in a way that if addiction occurs, it makes it harder to refrain from returning to addiction related behaviors.
Study reveals binge drinking is associated with more widespread neural dysfunction than previously believed. In those who binge drink, the visual areas of the brain show unusually high levels of activation. Additionally, those who binge drink have more difficulty in feeling empathy for others.
Researchers hypothesize vitamin B1 (thiamine) deficiency may play a significant role in dementia associated with alcohol use disorder. It is known iron deposits in the brain contribute to neurodegenerative diseases. Those with AUD have elevated levels of both iron in their blood and thiamine deficiency. Thiamine is vital for maintaining the blood-brain barrier. Thiamine deficiency associated with AUD disrupts the integrity of the BBB, allowing for more iron deposits within the brain and leading to oxidative tissue damage.
