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          alcohol use disorder

          This shows a glass of scotch.
          FeaturedNeurosciencePsychology
          ·March 29, 2024·5 min read

          Compound May Curb Alcohol Dependence

          The compound LY2444296, which blocks the kappa opioid receptor, significantly reduces alcohol consumption in animal models of alcohol dependence. This study suggests LY2444296 could be a breakthrough in treating alcohol use disorder (AUD) by targeting the brain's KOP system, implicated in addiction and withdrawal symptoms.
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          This shows a woman and a drink.
          FeaturedNeurosciencePsychology
          ·March 21, 2024·6 min read

          Targeting Stress Neurons Could Curb Problem Alcohol Use

          Researchers made a significant discovery, identifying that inhibiting neurons related to stress responses may decrease alcohol consumption in individuals suffering from post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD) simultaneously. Their study used a rat model to demonstrate that reducing the activity of corticotropin-releasing factor (CRF) producing neurons in the central amygdala lessens alcohol intake without affecting trauma-related anxiety.
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          This shows a map and glasses of drink.
          FeaturedGeneticsNeuroscience
          ·December 26, 2023·4 min read

          Global Genetic Insights into Problematic Alcohol Use

          A new study uncovers a shared genetic basis for problematic alcohol use (PAU) across diverse ancestries. This research broadens our understanding of PAU's genetic architecture and its consequences, including its role as a major cause of health problems and death.
          Read More
          This shows a man and empty drinking glasses.
          FeaturedGeneticsNeurosciencePsychology
          ·December 1, 2023·4 min read

          Peptide PACAP’s Key Role in Alcohol Addiction

          Alcohol, the world's most common addictive substance, leads to $249 billion in annual costs and 88,000 deaths in the U.S. Alcohol use disorder affects millions but is under-treated. Researchers discovered a key player in alcohol addiction: pituitary adenylate cyclase activating polypeptide (PACAP).
          Read More
          This shows a kid drinking soda.
          FeaturedNeurosciencePsychology
          ·November 8, 2023·5 min read

          Soda’s Slippery Slope to Alcohol Use in Kids

          A recent study points to a potential link between regular caffeinated soda consumption in children and an increased likelihood of alcohol use. Delving into over 2,000 young participants' habits, researchers found a connection to impulsivity and working memory deficits.
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          This shows a man holding his head.
          FeaturedNeurologyNeuroscience
          ·October 31, 2023·4 min read

          Hormonal Link in Alcohol Withdrawal Headaches

          Alcohol use disorder impacts 283 million individuals globally, with limited therapeutic options. Researchers discovered a significant connection between the stress hormone, corticotropin-releasing factor (CRF), and alcohol-withdrawal headaches.
          Read More
          This shows a woman with glasses of wine and a plate of food.
          FeaturedGeneticsNeurosciencePsychology
          ·September 18, 2023·5 min read

          Genetic Link Between Eating Disorders and Alcohol Use Discovered

          A comprehensive study of adolescent twins unveils a genetic nexus between disordered eating and alcohol use disorders (AUDs). This correlation underscores worse outcomes, including fatality, especially when these conditions manifest simultaneously in younger teens.
          Read More
          This shows glasses and genes.
          FeaturedGeneticsNeuroscience
          ·July 17, 2023·5 min read

          Neuronal Plasticity Genes Linked to Alcohol Use Disorders

          A new study discovered a link between alcohol use disorders (AUDs) and alteration of a group of genes known to influence neuronal plasticity and pain perceptions. The team used three distinct animal models to identify the genes responsible for drinking behaviors.
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          This shows a head made out of bottles.
          FeaturedNeurosciencePsychology
          ·June 19, 2023·8 min read

          Alcohol Use Disorder: More Alcohol, More Impairment, Regardless of Drinking Habits

          Researchers reveal the idea of "holding one's liquor" is complex, particularly among heavy drinkers. The study shows that while individuals with alcohol use disorder (AUD) display less impairment after consuming a standard intoxicating dose, they exhibit significantly more impairment when the consumption aligns with their usual heavier drinking habits.
          Read More
          This shows a person awake late at night.
          FeaturedNeuroscience
          ·June 16, 2023·5 min read

          Night Owls’ Lifespan Less Linked to Sleep Patterns, More to Lifestyle Choices

          Recent research refutes the idea that 'night owls' face a shorter lifespan due to their late-night tendencies, emphasizing lifestyle factors like smoking and drinking as the more significant contributors. The study involved almost 23,000 twins from Finland, tracked over a period of 37 years.
          Read More
          This shows people drinking.
          FeaturedNeurosciencePsychology
          ·June 15, 2023·3 min read

          Heavy Drinkers Misjudge Impairment Levels: A Risky Perception

          Heavy drinkers' belief that they can 'hold their liquor' better than light drinkers has been challenged by a new study, revealing that this perceived tolerance may lead to risky decisions. The research showed that after consuming equivalent amounts of alcohol, heavy drinkers felt less impaired than their lighter-drinking counterparts.
          Read More
          This shows an older man and bottles.
          FeaturedNeurologyNeuroscience
          ·June 12, 2023·6 min read

          Alcohol in Excess Hastens Alzheimer’s Progression

          Repeated alcohol intoxication can speed up Alzheimer’s disease progression associated with a genetic predisposition. The research demonstrated that mice exposed to consistent alcohol intoxication showed cognitive decline about two months earlier than typically expected.
          Read More
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          A 3D digital rendering showing a developing fetal brain connected by glowing neural pathways and floating DNA strands, surrounded by subtle immune cells.

          How Severe Illness During Pregnancy Alters Fetal Brain Development

          A 3D digital illustration of a human brain side-by-side comparison, highlighting the language centers glowing brightly and equally in both a younger and older brain, while executive function areas are dimmed in the older brain.

          Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

          Rejuvenation of Microglia by Youth Protein TIMP2 in the Aging Brain

          Youth Protein TIMP2 Restores Immune Function in the Aging Brain

          A multi-panel documentary photo. Left: A Black man sits alone on a locker room bench with his head down. Center: A Latino man sits withdrawn at a family kitchen table. Right: A White man looks thoughtfully at wellness pamphlets in a public waiting area. All convey isolation.

          Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

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