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Genetics

Genetics articles related to neuroscience research will be listed here.

Featured Genetics Neurology Neuroscience

·February 16, 2026·9 min read

Two Genetic “Hits” Required to Trigger Parkinson’s Neurodegeneration

Researchers find that a mutation in GBA1 must be paired with an ATP13A2 mutation to drive the neurodegeneration seen in Parkinson’s disease.

This shows DNA coming out of a neuron, representing this article states the link between neuroscience and genetics in memory research.

Featured Genetics Neuroscience

·February 15, 2026·7 min read

Neural Reprogramming Restores “Young” Memory in Aging Brains

Researchers use partial cellular reprogramming to rejuvenate "engram" neurons, successfully restoring memory in aged and Alzheimer's-model mice.

Brain Cancer Featured Genetics Neurology Neuroscience

·February 14, 2026·9 min read

Brain Tumor Pressure Triggers Neuron Death Pathways

It's not just the cancer that kills, it's the pressure. Scientists have discovered that physical force on the brain triggers a genetic "suicide" switch in healthy neurons.

This shows glowing neurons, as though they are the target scientists discovered.

Featured Genetics Neurology Neuroscience

·February 12, 2026·8 min read

New Drug Target Could Freeze Alzheimer’s in Its Tracks

Is the IDOL enzyme the key to stopping Alzheimer's? New research shows that blocking this single target can dissolve brain plaques and boost cognitive resilience. By lowering the brain's "strongest risk factor" protein, scientists have found a new way to keep neurons communicating even under attack.

Illustration of chandelier cells connecting to pyramidal neurons in the brain.

Featured Genetics Neurology Neuroscience

·January 13, 2026·3 min read

Brain Conductors Find Precise Connection to Target Cells via Protein Handshake

Researchers identify two key proteins that allow chandelier cells to connect with excitatory neurons. This "handshake" regulates brain signals and, when disrupted, may lead to epilepsy or autism.

This shows DNA and other cellular factors associated with ASD.

Autism Featured Genetics Neuroscience

·December 10, 2025·9 min read

Many Autism Cases May Be Preventable

A new study proposes that autism arises when genetic vulnerability, an early environmental trigger, and prolonged activation of the cellular stress response align during critical developmental windows. This “three-hit” metabolic model reframes autism as a disorder of disrupted cellular communication and energy metabolism rather than an inevitable genetic outcome.

Featured Genetics Neuroscience

·December 9, 2025·7 min read

Key Brain Protein Controls How We Learn Reward Cues

Changing levels of the brain protein KCC2 can alter how reward associations form, reshaping the learning process that links cues to outcomes. Reduced KCC2 activity increased dopamine neuron firing and strengthened new cue–reward connections, offering insight into how addictions and maladaptive habits develop.

Featured Genetics Neurology Neuroscience

·December 6, 2025·7 min read

Blocking a Key Protein Greatly Reduces Alzheimer’s Damage

New findings show that removing Centaurin-α1, a protein elevated in Alzheimer’s disease, significantly reduces inflammation, plaque buildup, and cognitive deficits in a well-established mouse model. Eliminating this protein normalized several brain pathways, protected neural connections in the hippocampus, and improved spatial learning.

Featured Genetics Neuroscience

·December 5, 2025·5 min read

Astrocytes Found to Drive Key Brain Changes in Nicotine Addiction

New research shows that astrocytes play an active role in nicotine-induced brain changes, challenging the long-held neuron-centered view of addiction. Nicotine stimulates receptors on astrocytes, triggering signaling cascades that boost glutamine synthetase activity and amplify glutamate-related pathways.

This shows a child and parent walking in a "forest" of DNA.

Featured Genetics Neurology Neuroscience

·December 4, 2025·7 min read

Mutation in Key Enzyme Triggers Ferroptosis and Childhood Dementia

Researchers have identified how a single mutation in the GPX4 enzyme causes neurons to undergo ferroptosis, leading to severe early-onset dementia. The study provides the first molecular evidence that ferroptosis can directly drive neurodegeneration in the human brain.

This shows a child reaching to touch neurons.

Featured Genetics Neuroscience

·December 3, 2025·6 min read

Early-Life Stimulation Switches On a Molecular Code for Memory

New research shows that childhood environments shape lifelong memory through a single molecular switch that controls learning-related gene activity. In animal models, enriched early experiences activated this switch, strengthening neural circuits involved in memory and cognition, while deprived environments suppressed it.

Featured Genetics Neuroscience

·December 3, 2025·7 min read

Hidden Brain Layers Revealed in Key Memory Center

Scientists have identified a previously unseen layered organization inside one of the brain’s most important memory hubs. The CA1 region of the hippocampus was found to contain four distinct bands of neuron types, each defined by unique genetic signatures that shift subtly across the structure.

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Genetics

Two Genetic “Hits” Required to Trigger Parkinson’s Neurodegeneration

Neural Reprogramming Restores “Young” Memory in Aging Brains

Brain Tumor Pressure Triggers Neuron Death Pathways

New Drug Target Could Freeze Alzheimer’s in Its Tracks

Brain Conductors Find Precise Connection to Target Cells via Protein Handshake

Many Autism Cases May Be Preventable

Key Brain Protein Controls How We Learn Reward Cues

Blocking a Key Protein Greatly Reduces Alzheimer’s Damage

Astrocytes Found to Drive Key Brain Changes in Nicotine Addiction

Mutation in Key Enzyme Triggers Ferroptosis and Childhood Dementia

Early-Life Stimulation Switches On a Molecular Code for Memory

Hidden Brain Layers Revealed in Key Memory Center

Brain’s Developmental Switch May Shape Lifelong Obesity Risk

Single DMT Dose Provides Lasting Relief from Depression

Brain Never Outgrows the Ability to Emotionally Evolve

Brain Swelling Reveals Alzheimer’s Treatment Success

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