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          UC Irvine

          This shows an eye.
          FeaturedNeuroscienceVisual Neuroscience
          ·May 8, 2023·5 min read

          Eye-Opening Drug Discovery May Help Treat Age-Related Macular Degeneration

          350 million people worldwide are believed to suffer from blinding diseases including age-related macular degeneration and diabetic retinopathy. Researchers have discovered a small class of drugs, dubbed SREDs, that have the potential to treat a range of blinding diseases.
          Read More
          This shows a burger
          FeaturedNeuroscience
          ·April 5, 2023·3 min read

          How to Prevent a High-Fat Diet From Throwing Metabolism Out of Whack

          Eliminating SAPS3 from the genome of mice allowed the AMPK protein complex to activate and maintain normal energy balance, even with high-fat meals. This discovery could pave the way for developing a new approach to metabolic disorders such as obesity, diabetes, and fatty liver disease.
          Read More
          This shows a brain
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·February 27, 2023·4 min read

          Early-Life Stress Can Disrupt Maturation of Brain’s Reward Circuits, Promoting Disorders

          Researchers have identified a novel stress-sensitive pathway in the reward system of the brain that releases corticotropin-releasing hormone in response to stress. Adverse experiences cause this pathway to become overactive.
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          This shows the outline of a head
          FeaturedGeneticsNeurologyNeuroscience
          ·January 30, 2023·5 min read

          How Our Brains Turn Into Smarter Disease Fighters

          CRISPR gene editing created the G795A amino acid which was introduced to microglia derived from human stem cells. Researchers were able to transplant the donor microglia immune cells into humanized rodent models while administering an FDA-approved cancer drug called pexidartinib. The inclusion of the amino acid cause the donated microglia to thrive and resist the drug, while the host microglia died. The findings open the door for new methods of using microglia to treat a range of neurodegenerative disorders.
          Read More
          This shows a head made of cogwheels
          FeaturedNeuroscience
          ·November 30, 2022·4 min read

          A Crucial Role of Brain’s Striatum Cilia in Time Perception

          Destruction or removal of the cilia in the striatum impairs time perception and judgment, new research suggests. The findings could have implications for a range of diseases including schizophrenia, ASD, and Parkinson's.
          Read More
          This shows the outline of a head
          FeaturedNeurologyNeuroscience
          ·November 30, 2022·4 min read

          Controversial Alzheimer’s Drug Approval Sparks Surprising Impact

          Media coverage of the FDA-approved Alzheimer's drug aducanumab made the public less willing to volunteer in Alzheimer's pharmaceutical trials.
          Read More
          This shows optic nerve slices
          FeaturedNeuroscienceVisual Neuroscience
          ·November 21, 2022·4 min read

          Repeated Stress Accelerates Aging of the Eye

          Stress such as intraocular pressure elevation in the eye causes the retinal tissue to undergo transcriptional and epigenetic changes similar to natural aging.
          Read More
          This shows eye glasses
          FeaturedGeneticsNeuroscienceVisual Neuroscience
          ·October 6, 2022·4 min read

          The Adult Brain Can Recover Lost Vision

          Administering a chemical compound called synthetic retinoids to the retina helped restore brain networks associated with vision and prompted the growth of two times more neurons, effectively restoring vision in adult mouse models of the genetic visual disorder LCA.
          Read More
          This shows the outline of a head
          FeaturedNeuroscience
          ·September 27, 2022·4 min read

          What Brings Our Senses and Thoughts Together?

          Study reveals the role the neocortex plays in our ability to think, recall events, and make decisions.
          Read More
          This shows an alarm clock
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·September 2, 2022·5 min read

          Circadian Rhythm Disruption Found to Be Common Among Mental Health Disorders

          Circadian rhythm disruption is a psychopathological factor shared by a broad range of mental illnesses.
          Read More
          This shows a head made of clocks
          FeaturedNeurosciencePsychology
          ·August 23, 2022·4 min read

          Distorted Time Perception During the Pandemic

          Many people report their perception of time felt distorted during the early stages of the COVID-19 pandemic, including problems in tracking the day of the week or feeling as though time was passing slower. Researchers say this temporal disintegration was, in part, associated with pandemic related stressors.
          Read More
          This shows the outline of a person
          FeaturedGeneticsNeurologyNeuroscience
          ·July 5, 2022·4 min read

          Study Links ALS to Immune and Central Nervous Systems

          Based on new findings, researchers say bone marrow transplants may be an effective treatment for ALS.
          Read More
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          This shows Macaque monkeys watching a video on a laptop.

          Familiar Faces and Fights: What Monkeys Like to Watch Most

          This shows a robot performing surgery.

          Robot Achieves Complex Surgery Autonomously Through AI Training

          This shows cancer cells.

          Cancer Pathway Found to Weaken Brain and Eye Barriers

          This shows a brain.

          Memory Chooses Meaning Over Surface Similarities

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