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UC Irvine

·July 20, 2021·3 min read

Unleashing Treg Cells May Lead to Treatments for Multiple Sclerosis

Piezo1 limits the potential of regulatory T cells (Treg) to mitigate autoimmune neuroinflammation. Inhibiting Piezo1 could lead to new treatments for autoimmune disorders like multiple sclerosis.

Featured Neurology Neuroscience

·May 15, 2021·5 min read

Low Sugar Metabolite Associated With Disability and Neurodegeneration in Multiple Sclerosis

Lower serum levels of the sugar metabolite GlcNAc was associated with progressive disability and neurodegeneration in patients with multiple sclerosis.

Featured Neurology

·October 7, 2020·3 min read

Simple Sugar Possible Therapy for Repairing Myelin in Multiple Sclerosis

N-acetylglucosamine, a simple sugar found in breast milk, promotes remyelination in mouse models of multiple sclerosis. The findings could have implications for treating multiple sclerosis in humans.

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Featured Open Neuroscience Articles Psychology

·September 19, 2020·3 min read

Rising Stress and Depression in Coronavirus-Related Losses and Media Consumption

Researchers link the rise in acute stress and depression rates in the U.S to multiple stressors, such as unemployment and coronavirus-related media consumption.

Featured Genetics Open Neuroscience Articles Psychology

·September 3, 2020·4 min read

Schizophrenia: Nurture Cannot Overcome Nature

Too much methionine in-vitro caused schizophrenia in mice, regardless of the level of postpartum care. Researchers suggest the same outcome would be true for humans.

Featured Neuroscience Open Neuroscience Articles

·July 14, 2020·3 min read

Pickled Capers Activate Proteins Important for Brain and Heart Health

Quercetin, a flavonoid found in pickled capers, modulates potassium ion channels in the KCNQ gene family. These channels are influential in human health, and their dysfunction is linked to diseases, including diabetes, epilepsy, and cardiac arrhythmias.

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·November 15, 2019·3 min read

New cell therapy improves memory and stops seizures following TBI

Transplanting embryonic progenitor interneurons into the hippocampus of mouse models of TBI, researchers noticed the neurons migrated to the injury site and made new connections. Following treatment, memory improved and seizures were reduced.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·October 1, 2019·3 min read

A brain protein that could put the brakes on Alzheimer’s

Reducing the expression of the protein TOM1 in mouse models of Alzheimer's disease increased the pathology, exacerbated cognitive problems, and raised levels of inflammation in the brain. Restoring TOM1 reversed the effects. Findings suggest a new therapeutic target for treating dementia.

Featured Neuroscience

·September 23, 2019·2 min read

Critical role of brain circuits in improving learning and memory revealed

A newly identified neural network in the hippocampal formation plays a critical role in memory and object-location learning. The findings are highly relevant to learning and memory disorders, including Alzheimer's disease.

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Featured Neuroscience

·August 30, 2019·3 min read

Diverse linguistic environment boosts brain sensitivity to new learning

Living in a linguistically diverse environment helps promote more effective learning of new languages for monolingual people.

Featured Neurology Neuroscience Open Neuroscience Articles

·August 21, 2019·3 min read

Link between brain immune cells and Alzheimer’s disease development identified

The brain's immune cells may contribute to the development of Alzheimer's disease. Turning off microglia in specific areas of the brain prevented the formation of amyloid plaques. The findings could help pave the way for new treatments for Alzheimer's.

Featured Neuroscience Open Neuroscience Articles

·August 19, 2019·3 min read

Online brain games can extend in-game ‘cognitive youth’ into old age

Playing online games which are mentally taxing can help older adults to reduce cognitive decline associated with aging. Older adults who played brain training games showed similar brain functionality as younger people who were less practiced at the games.

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