The brain's immune cells may contribute to the development of Alzheimer's disease. Turning off microglia in specific areas of the brain prevented the formation of amyloid plaques. The findings could help pave the way for new treatments for Alzheimer's.
N-acetylglucosamine, a simple sugar found in breast milk, promotes remyelination in mouse models of multiple sclerosis. The findings could have implications for treating multiple sclerosis in humans.
Long-term memory consolidation and short-term memory processes that occur during sleep do so at a cost to one another.
Transplanting embryonic progenitor interneurons into the hippocampus of mouse models of TBI, researchers noticed the neurons migrated to the injury site and made new connections. Following treatment, memory improved and seizures were reduced.
Playing online games which are mentally taxing can help older adults to reduce cognitive decline associated with aging. Older adults who played brain training games showed similar brain functionality as younger people who were less practiced at the games.
Skin and liver cells appear to have their own circadian clock. Both the liver and skin respond to changes in light and maintain critical function, independent of the brain's circadian rhythm.
A molecular process caused by the TREM2 gene mutation in the brain's microglia increases the risk of Alzheimer's disease, a new study reports.
Study identifies a novel neural circuit that regulates spatial learning and memory in the brain's hippocampal formation.
Reducing the expression of the protein TOM1 in mouse models of Alzheimer's disease increased the pathology, exacerbated cognitive problems, and raised levels of inflammation in the brain. Restoring TOM1 reversed the effects. Findings suggest a new therapeutic target for treating dementia.