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          UC Irvine

          This shows an old lady
          FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles
          ·October 1, 2019·3 min read

          A brain protein that could put the brakes on Alzheimer’s

          Reducing the expression of the protein TOM1 in mouse models of Alzheimer's disease increased the pathology, exacerbated cognitive problems, and raised levels of inflammation in the brain. Restoring TOM1 reversed the effects. Findings suggest a new therapeutic target for treating dementia.
          Read More
          This shows a head made of cogwheels
          FeaturedNeuroscience
          ·November 30, 2022·4 min read

          A Crucial Role of Brain’s Striatum Cilia in Time Perception

          Destruction or removal of the cilia in the striatum impairs time perception and judgment, new research suggests. The findings could have implications for a range of diseases including schizophrenia, ASD, and Parkinson's.
          Read More
          Image shows a person undergoing acupuncture.
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·October 31, 2016·2 min read

          Acupuncture Lowers Hypertension by Activating Natural Opioids

          Researchers successfully used electroacupuncture to increase the gene expression of enkephalins and reduce blood pressure for three days.
          Read More
          This shows two older men.
          FeaturedNeurologyNeuroscience
          ·May 24, 2023·4 min read

          Alzheimer’s Pathology Found in Superagers With Superior Cognition

          A new study found people who are 90+ and have superior cognitive skills have similar levels of brain pathology as Alzheimer's patients. However, they also have less brain pathology of other neurodegenerative diseases. The researchers are now looking at how lifestyle habits and health conditions are associated with superior cognition in individuals who are 90+.
          Read More
          This shows a bunch of cliantro
          FeaturedNeurologyNeuroscience
          ·July 22, 2019·3 min read

          Anticonvulsant mechanism of cilantro uncovered

          Study reveals a molecular action that enables cilantro to effectively delay seizures. One component of cilantro, dodecenal, binds to a specific part of the potassium channel to open them, reducing cellular excitability.
          Read More
          This shows pills and a person walking.
          FeaturedNeurosciencePsychology
          ·July 6, 2026·12 min read

          Biomarkers Boost Antidepressant Success Rates by 67%

          A new study demonstrates that combining fMRI brain connectivity, cognitive reward testing, and clinical markers to guide antidepressant selection increases patient response rates by nearly 67%.
          Read More
          This shows the researcher next to a head made of clocks
          FeaturedNeuroscience
          ·May 30, 2019·3 min read

          Body parts respond to day and night independently from brain

          Skin and liver cells appear to have their own circadian clock. Both the liver and skin respond to changes in light and maintain critical function, independent of the brain's circadian rhythm.
          Read More
          This shows a woman looking at a brain model.
          FeaturedNeuroscience
          ·November 15, 2024·4 min read

          Brain Circuits for Spatial Memory and Navigation Identified

          Researchers have identified two neural circuits in the retrosplenial cortex (RSC) that are critical for spatial navigation and memory storage. The M2-projecting pathway links spatial thought to action, while the AD-projecting pathway supports location-specific memory.
          Read More
          This shows a brain model.
          FeaturedNeuroscience
          ·February 14, 2024·4 min read

          Brain Mapping With Novel Rabies Viral Vectors

          Researchers developed 20 novel recombinant rabies viral vectors that present unparalleled advantages for neural circuit mapping in aging and Alzheimer’s disease studies. These vectors are engineered to highlight microstructural changes in brain neurons through enhanced fluorescent proteins, offering insights into neural networks at both micro and macro scales.
          Read More
          This shows a brain.
          FeaturedNeurologyNeuroscience
          ·October 6, 2025·6 min read

          Brain’s Shape Could Reveal the Earliest Signs of Alzheimer’s

          A groundbreaking study reveals that aging alters not just the size but the shape of the human brain, reshaping regions in ways linked to memory and reasoning decline. Researchers found that as people age, the lower and front areas of the brain expand outward, while the upper and back regions compress inward.
          Read More
          This shows an alarm clock
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·September 2, 2022·5 min read

          Circadian Rhythm Disruption Found to Be Common Among Mental Health Disorders

          Circadian rhythm disruption is a psychopathological factor shared by a broad range of mental illnesses.
          Read More
          This shows the outline of a head
          FeaturedNeurologyNeuroscience
          ·November 30, 2022·4 min read

          Controversial Alzheimer’s Drug Approval Sparks Surprising Impact

          Media coverage of the FDA-approved Alzheimer's drug aducanumab made the public less willing to volunteer in Alzheimer's pharmaceutical trials.
          Read More
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          This shows a mother and baby. Caption reads "parenting, caregiving, neural circuits, motivation, resource scarcity."

          Resource Scarcity Alters Maternal Brain Activity to Hinder Caregiving

          This shows neurons.

          Existing Drug Could Halt Brain Inflammation in Alzheimer’s

          This shows a brain made of food. Caption reads "Ultraprocessed Foods Hijack Brain Reward Centers."

          Ultraprocessed Foods Alter Insulin and Brain Reward Responses

          This shows a woman playing chess, a brain and a light switch.

          Optogenetics Pioneers Win 2026 Nobel Prize in Physiology or Medicine

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