Researchers say findings about how dopamine affects the initiation of movement could pave the way for the development of new treatments for Parkinson's and other movement related disorders.
Max Planck researchers have made a groundbreaking discovery that helps explain why people with Parkinson's often report an impaired sense of smell. They discovered the total volume of glomeruli in the olfactory bulb of Parkinson's patients is only half of that found in people without the disease.
Researchers have implicated an enzyme that appears to make both Tau and alpha synculein more toxic in Alzheimer's and Parkinson's disease. Inhibiting this enzyme has already proved helpful in treating animal models of Alzheimer's disease. The researchers report they are moving on to testing drugs that inhibit AEP in animal models of Parkinson's disease.
A neuroimaging study reports dopamine activity does not reflect the number of dopamine neurons in the substantia nigra of people with Parkinson's disease.
Mice that carry a gene associated with red hair have reduced production of dopamine in the substantia nigra and are more susceptible to toxins that can damage these dopaminergic neurons.
A new neuroimaging study finds iron is distributed in an unusual way in the brains of people with Parkinson's disease.
A new study provides insight into the areas of the brain which become activated when people are presented with aversive foods and suggests the reward circuit may encode disgust.