New Technique Helps Uncover Changes in ALS Neurons
A new method reveals some ALS affected neurons display hypo-excitability. Researchers say these changes most likely represent early steps in the disease progression.... Read More...
SOD1
ALS Treatment Delays Disease and Extends Life: Mouse Study
Researchers report transplanting altered neural stem cells into the brains of mice genetically engineered to exhibit symptoms of ALS, delayed the progression of the disease and extended lifespan.... Read More...
Large Aggregates of ALS Causing Protein Might Help Brain Cells
Researchers report the formation of larger, more visible SOD1 aggregates may help to protect brain cells.... Read More...
First Step Toward CRISPR Cure For ALS
UC Berkeley researchers report they have successfully used CRISPR-Cas9 gene editing to delay symptoms and extend lifespan in mouse models of ALS.... Read More...
Resolving Traffic Jams in Human ALS Motor Neurons
Researchers have generated motor neurons from people with familial ALS who carry FUS mutations.... Read More...
Malaria Drug Lowers Levels of ALS Linked Biomarker
According to researchers, a drug that has been used for decades to help treat malaria can lower levels of a biomarker associated with ALS.... Read More...
Common Protein Abnormality Pinpointed in Parkinson’s and ALS
Study implicates abnormalities in SOD1 with Parkinson's disease and ALS.... Read More...
Antidepressants May Enhance Drug Delivery to Brain
A new study reports an antidepressant temporarily inhibits the blood-brain barrier, allowing drugs to enter the brain. The findings could have implications for treating neurological diseases from ALS to epilepsy.... Read More...
Protective Molecule Sidelined in Models of ALS
Researchers have identified a naturally occurring molecule that has the potential for preserving sites of communication between nerves and muscles in ALS.... Read More...
Collapse of Mitochondria-Associated Membrane in ALS
Researchers report a collapse of the mitochondria-associated membrane is a common halmark in two genetic forms of ALS.... Read More...
Oligodendrocytes Induce Motor Neuron Death in ALS
A new study reports oligodendrocytes induce motor neuron death in ALS.... Read More...
Researchers Reverse Protein Clumping Involved in ALS
A new study reveals stabilizing the SOD1 protein can help reverse protein clumping in neurons affected by ALS.... Read More...