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Scripps Research Institute

·April 28, 2023·5 min read

Insomnia Drug Belsomra May Help Treat Opioid Addiction

A preclinical study found that suvorexant (Belsomra), an insomnia drug, could be a potential treatment for opioid use disorder (OUD) in rats. If the results are replicated in humans, the drug could offer a promising treatment for the millions of people with OUD and reduce drug intake and block relapse.

Featured Neurology Pain

·April 22, 2023·5 min read

Alcohol Fuels Pain: Study Reveals Link Between Drinking and Chronic Pain

Chronic alcohol consumption can increase sensitivity to pain through two molecular mechanisms. Researchers also identified potential new drug targets for treating alcohol-related chronic pain. Over half of people with alcohol use disorder (AUD) suffer from persistent pain, including alcoholic neuropathy. The study found that alcohol withdrawal could result in neuropathy that was not reversed by re-exposure to alcohol.

Featured Neuroscience

·March 6, 2023·5 min read

How Heavy Alcohol Consumption Increases Brain Inflammation

The immune signaling molecule interleukin 1B (IL-1B) is present at higher levels in mouse models of alcohol use disorder. The IL 1B pathway plays a different role in animal models of AUD, causing inflammation in brain areas that play a critical role in decision-making.

Featured Neurology Neuroscience

·December 14, 2022·6 min read

Discovery Could Explain Why Women Are More Likely to Get Alzheimer’s

Complement C3, a chemically modified form of an inflammatory immune protein, was more abundant in post mortem brain tissue of women who died from Alzheimer's disease than in males.

Featured Neuroscience Psychology

·November 18, 2022·5 min read

Can Pharmacotherapies Prevent Alcohol Use Disorder in People With PTSD?

Those with PTSD are almost twice as likely to develop alcohol use disorder than their peers who have not experienced trauma. Researchers report drugs that block FKBP5, such as benztropine, a drug used to control symptoms of Parkinson's disease, and the experimental compound SAFit2 reduce alcohol preference and drinking in models of PTSD.

Featured Genetics Neuroscience

·July 28, 2022·5 min read

New “Origins of Life” Chemical Reactions Discovered

Researchers discovered a new set of chemical reactions that use cyanide, ammonia, and carbon dioxide generates amino acids and nucleic acids, the building blocks of proteins and DNA.

Featured Genetics Neuroscience

·June 22, 2022·4 min read

Scientists Identify Sensor Underlying Mechanical Itch Stimulus

Study identifies a specific protein in sensory neurons that detects mechanical itch stimuli such as an insect crawling on the skin or when one touches an object that irritates the skin.

Featured Neuroscience Open Neuroscience Articles

·June 8, 2022·5 min read

Immune Protein May Drive Alcoholism Relapse

An immune protein called CSF1 may contribute to feelings of anxiety as a result of alcohol withdrawal for those with alcohol use disorder.

Featured Neuroscience Open Neuroscience Articles

·March 27, 2022·5 min read

Scientists Hunt for Neurons Responsible for Alcohol Withdrawal

Researchers reveal the role corticotropin-releasing factor produced by neurons plays in alcohol withdrawal symptoms.

This shows the structure of Flycatcher1, the protein discussed in the article

Featured Neuroscience Open Neuroscience Articles

·February 17, 2022·5 min read

Scientists Reveal How Venus Fly Traps Snaps Shut

Researchers have revealed the 3d structure of the Flycatcher1 protein channel which enables the Venus flytrap to close in response to prey. The findings shed light on how other mechanosensitive ion channels may operate in other plants, bacteria, and the human body.

Featured Neurology Neuroscience

·February 1, 2022·4 min read

Compound in the Herb Rosemary May Be Useful Against COVID-19 and Other Inflammatory Diseases

Carnosic acid, a compound found in the herb rosemary, can block the interaction with the COVID-19 SARS_CoV_2 spike protein and ACE2, the protein receptor the virus uses to gain access into cells. The compound appears to have anti-inflammatory effects and has previously been associated with a reduction in Alzheimer's symptoms.

This shows proteins in the retinal cells

Featured Neuroscience

·January 31, 2022·4 min read

A New Type of Cellular Communication in the Brain

Researchers have identified hundreds of proteins that are consistently transported throughout the healthy brain via small membrane-enclosed sacs. The findings reveal a new form of communication between brain cells.

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Scripps Research Institute

Insomnia Drug Belsomra May Help Treat Opioid Addiction

Alcohol Fuels Pain: Study Reveals Link Between Drinking and Chronic Pain

How Heavy Alcohol Consumption Increases Brain Inflammation

Discovery Could Explain Why Women Are More Likely to Get Alzheimer’s

Can Pharmacotherapies Prevent Alcohol Use Disorder in People With PTSD?

New “Origins of Life” Chemical Reactions Discovered

Scientists Identify Sensor Underlying Mechanical Itch Stimulus

Immune Protein May Drive Alcoholism Relapse

Scientists Hunt for Neurons Responsible for Alcohol Withdrawal

Scientists Reveal How Venus Fly Traps Snaps Shut

Compound in the Herb Rosemary May Be Useful Against COVID-19 and Other Inflammatory Diseases

A New Type of Cellular Communication in the Brain

Hitching a Ride: mRNA’s Transport System in Brain Cells Revealed

Shaping Young Minds: Neurodevelopment Interventions for Psychiatric Disorders

Ultra-Processed Foods: AI’s New Contribution to Nutrition Science

Aging Myelin: A New Perspective in Alzheimer’s Disease Progression

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