A defective protein quality control system leads to motor neuron death associated with disorders like ALS. Read More
Study reveals how two neural circuits dictate the choice between social approach and avoidance. The network connecting the infralimbic cortex to the basolateral amygdala (BLA) impairs social behavior if there is a decrease in neural activity. Another network connecting the prelimbic cortex to the BLA similarly impairs social behavior if the neural activity is increased. Read More
Study reveals up to 45% of people infected with COVID-19 were asymptomatic. The findings suggest asymptomatic infections likely played a significant role in the early and ongoing spread of coronavirus. Read More
Exposure to anesthesia causes lipid clusters to move from an ordered state to a disordered one, then back again. These changes lead to subsequent effects that cause changes in consciousness. Read More
Involuntary movements and tremors caused as a result of taking dopamine replacement medications for Parkinson's disease can be alleviated through the suppression of RasGRP1. Read More
An over-production of eIF4E impairs microglial cells, hampering their ability to effectively prune synapses and leading to autism-like behaviors in male mouse models of ASD. Read More
Structural mapping of both SARS and SARS-CoV-2, the virus that causes COVID-19, reveals an almost identical site on both coronaviruses to which the CR3022 antibody binds. This suggests a functionally important and vulnerable site for this family of coronaviruses. Read More
The FDA has approved a new drug named Ozanimod for the treatment of multiple sclerosis. Ozanimod binds to receptors in lymphocytes' surfaces, preventing them from reaching the brain. As the number of active lymphocytes decreases, the attack on the immune system diminishes. Read More
Fruit fly study reveals suppression of a genetic switch boosts long-term memory. Read More
Researchers have identified a set of drug-like compounds, including a common ingredient in throat lozenges, that can help protect mitochondria from the stresses associated with neurodegenerative diseases. Read More
The severity of Charcot-Marie-Tooth disease is linked to the degree to which the aminoacyl-tRNA synthetases enzyme is relaxed or extended. Read More
Exosomes carry signaling information required to regulate neural circuit development. Read More
