Complement C3, a chemically modified form of an inflammatory immune protein, was more abundant in post mortem brain tissue of women who died from Alzheimer's disease than in males.
Those with PTSD are almost twice as likely to develop alcohol use disorder than their peers who have not experienced trauma. Researchers report drugs that block FKBP5, such as benztropine, a drug used to control symptoms of Parkinson's disease, and the experimental compound SAFit2 reduce alcohol preference and drinking in models of PTSD.
Researchers discovered a new set of chemical reactions that use cyanide, ammonia, and carbon dioxide generates amino acids and nucleic acids, the building blocks of proteins and DNA.
Study identifies a specific protein in sensory neurons that detects mechanical itch stimuli such as an insect crawling on the skin or when one touches an object that irritates the skin.
Researchers reveal the role corticotropin-releasing factor produced by neurons plays in alcohol withdrawal symptoms.
Researchers have revealed the 3d structure of the Flycatcher1 protein channel which enables the Venus flytrap to close in response to prey. The findings shed light on how other mechanosensitive ion channels may operate in other plants, bacteria, and the human body.
Carnosic acid, a compound found in the herb rosemary, can block the interaction with the COVID-19 SARS_CoV_2 spike protein and ACE2, the protein receptor the virus uses to gain access into cells. The compound appears to have anti-inflammatory effects and has previously been associated with a reduction in Alzheimer's symptoms.
Researchers have identified hundreds of proteins that are consistently transported throughout the healthy brain via small membrane-enclosed sacs. The findings reveal a new form of communication between brain cells.
Researchers have determined the near-atomic scale structure of the anxiety-associated GPR158 receptor. The findings enable an avenue to create potential therapeutics to block the receptor in order to treat depression, stress, and other mental health disorders.