Scripps Research Institute

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Scripps Research Institute

Autism Featured Neuroscience Open Neuroscience Articles

·July 14, 2020

Autism Researchers Map Brain Circuitry of Social Preference

Study reveals how two neural circuits dictate the choice between social approach and avoidance. The network connecting the infralimbic cortex to the basolateral amygdala (BLA) impairs social behavior if there is a decrease in neural activity. Another network connecting the prelimbic cortex to the BLA similarly impairs social behavior if the neural activity is increased. Read More

Featured Neuroscience Neuroscience Videos Open Neuroscience Articles

·June 12, 2020

Up to 45 percent of COVID-19 infections may be asymptomatic

Study reveals up to 45% of people infected with COVID-19 were asymptomatic. The findings suggest asymptomatic infections likely played a significant role in the early and ongoing spread of coronavirus. Read More

Featured Neurology Neuroscience Open Neuroscience Articles

·May 29, 2020

Anesthesia’s effect on consciousness solved, settling century-old scientific debate

Exposure to anesthesia causes lipid clusters to move from an ordered state to a disordered one, then back again. These changes lead to subsequent effects that cause changes in consciousness. Read More

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Featured Genetics Neurology Neuroscience

·May 1, 2020

Parkinson’s dyskinesia mechanism explained

Involuntary movements and tremors caused as a result of taking dopamine replacement medications for Parkinson's disease can be alleviated through the suppression of RasGRP1. Read More

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·April 15, 2020

Autism in males linked to defect in brain immune cells and microglia

An over-production of eIF4E impairs microglial cells, hampering their ability to effectively prune synapses and leading to autism-like behaviors in male mouse models of ASD. Read More

Featured Neuroscience

·April 4, 2020

Clues to COVID-19 coronavirus’s vulnerability emerge from an antibody against SARS

Structural mapping of both SARS and SARS-CoV-2, the virus that causes COVID-19, reveals an almost identical site on both coronaviruses to which the CR3022 antibody binds. This suggests a functionally important and vulnerable site for this family of coronaviruses. Read More

Featured Neurology Neuroscience

·March 28, 2020

FDA approves ozanimod for treatment of multiple sclerosis

The FDA has approved a new drug named Ozanimod for the treatment of multiple sclerosis. Ozanimod binds to receptors in lymphocytes' surfaces, preventing them from reaching the brain. As the number of active lymphocytes decreases, the attack on the immune system diminishes. Read More

Featured Genetics Neuroscience

·January 13, 2020

Long-term memory performance depends upon gating system

Fruit fly study reveals suppression of a genetic switch boosts long-term memory. Read More

Electrophysiology Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·January 12, 2020

Neurons’ energy organelle protected from damage linked to ALS & Alzheimer’s

Researchers have identified a set of drug-like compounds, including a common ingredient in throat lozenges, that can help protect mitochondria from the stresses associated with neurodegenerative diseases. Read More

Featured Genetics Neurology Neuroscience

·September 30, 2019

‘Relaxed’ enzymes may be at the root of Charcot-Marie-Tooth disease

The severity of Charcot-Marie-Tooth disease is linked to the degree to which the aminoacyl-tRNA synthetases enzyme is relaxed or extended. Read More

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·July 22, 2019

Exosomes may hold the answer to treating and diagnosing developmental brain disorders

Exosomes carry signaling information required to regulate neural circuit development. Read More

Featured Genetics Neuroscience Psychology

·June 19, 2019

Overcoming PTSD: Study reveals memory disruption drug target

Levels of a key molecule are elevated in the amygdala of both humans and mouse models of PTSD. The microRNA, mir-135b-5p, may be a novel biomarker for treating the disorder. Read More

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