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remyelination

·November 6, 2020·4 min read

New Strategies for Restoring Myelin on Damaged Nerve Cells

Researchers have discovered a two-pronged approach to restore myelin on regenerated axons in a mouse model of optic nerve damage. The findings have positive implications for the treatment of multiple sclerosis.

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·October 7, 2020·3 min read

Simple Sugar Possible Therapy for Repairing Myelin in Multiple Sclerosis

N-acetylglucosamine, a simple sugar found in breast milk, promotes remyelination in mouse models of multiple sclerosis. The findings could have implications for treating multiple sclerosis in humans.

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·August 24, 2020·5 min read

Mechanisms Identified to Restore Myelin Sheaths After Injury or in Multiple Sclerosis

eEF1a1 activated by acetylation prevents remyelination, but if the protein is deactivated by deacetylation, myelin sheaths can be rebuilt. The findings shed light on the process of remyelination and could provide avenues of treatment for multiple sclerosis, and other conditions associated with demyelination.

This shows the myelin regrowth on neurons

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·April 25, 2019·3 min read

Stem cells from hair follicles have potential to repair myelin sheath in mice

Melanocyte stem cells from human hair follicles that carry CD34 have the ability to turn into glial cells. The CD34+ stem cells can regenerate myelin, both on neurons and in mouse models with a genetic defect that prevents the formation of healthy myelin sheaths. The findings could have positive implications for the treatment of demyelinating diseases, such as Multiple Sclerosis.

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·April 18, 2019·5 min read

Study shows promise in repairing damaged myelin

A study in mouse models of multiple sclerosis demonstrates a compound called sobetirome promotes remyelination, and a derivative of the compound can penetrate the blood-brain barrier to enable a tenfold increase in infiltration to the CNS. Researchers are confident their research will translate from mice into humans, providing a new avenue of treatment for MS.

Featured Genetics Neurology

·January 23, 2019·4 min read

Old Cells Repair Damage in Brains of Those with Multiple Sclerosis

Researchers discovered oligodendrocyte neurogenesis is limited in the brains of patients with Multiple Sclerosis. However, oligodendrocytes that survive the autoimmune attack associated with MS may be able to form new myelin.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·December 18, 2018·4 min read

Study Reveals What May Prevent Remyelination

Study reveals PRRX1 gene expression results in cell cycle arrest and quiescence of oligodendrocyte progenitors, blocking myelin production.

Featured Neurology Neuroscience

·August 27, 2018·3 min read

Possible New Ways to Regenerate Myelin

Researchers successfully used a synthetic compound to stimulate a receptor pathway to promote remyelination in the brain. The technique may have significant beneficial implications for treating multiple sclerosis, researchers say.

Featured Genetics Neurology

·November 3, 2017·6 min read

Blood Clotting Protein Prevents Repair in the Brain

A new study sheds light on demylination diseases like Multiple Sclerosis. Researchers discovered a blood clotting protein can leak into the central nervous system and prevent myelin production.

Featured Neurology

·October 24, 2017·5 min read

A Little Myelin Goes A Long Way To Restore Nervous System Function

Renewed, thin myelin sheaths are sufficient to help restore nervous system impairments in diseases like multiple sclerosis, a new study in PNAS reports.

Featured Neurology Open Neuroscience Articles

·October 11, 2017·8 min read

Allergy Drug Improves Function in Patients with Chronic Injury from Multiple Sclerosis

UCSF researchers reveal a common over the counter antihistamine appears to accelerate neural signaling and restore nervous system functioning for some multiple sclerosis patients.