While the effects of hallucinogens to treat mental illnesses are being researched, little is known about the neurobiology of those who dabble in psychedelics for recreational purposes. A new study reports "psychonauts" have distinct behaviors, including taking a scientific approach to documenting their experience with hallucinogens, compared to more recreational users.
Gene expression patterns in four regions of the prefrontal cortex are distinctly different in those who have been diagnosed with PTSD compared to those who have not. Major differences were seen in interneurons, which inhibit the immune system and microglia in the central nervous system. Findings shed light on why women are more likely to experience PTSD and compound a link between post-traumatic stress and a dampening of the immune system.
Focusing on gene changes as a result of epigenetic processes, such as aging, researchers were able to reverse elevated levels of harmful genes associated with memory deficits in Alzheimer's disease.
Anterior cingulate cortex neurons project connections to the superior colliculus. The superior colliculus carries out reflexive movements. The study finds the purpose of the ACC neurons connections to the SC is to over-rider the SC when executive control is essential.
Study concludes one reason we may make unwise decisions is our preference for a positive outcome.
Study identifies a key role locus coeruleus neurons play in attentional control.