The HDAC9 enzyme appears to play a critical role in learning and neural communication. Decreased expression of HDAC9 in the hippocampus and prefrontal cortex has been noted in patients with Alzheimer's disease. Researchers say HDAC9 may be a regulator of synaptic plasticity.
Researchers discover elevated levels of TG2 in the prefrontal cortex of people who committed suicide.
Researchers propose a new framework for three seemingly unconnected forms of creativity.
Obese children tend to have a thinner prefrontal cortex and cerebral cortex. The findings could explain why there is a correlation between obesity in children and decreased executive function.
Study concludes one reason we may make unwise decisions is our preference for a positive outcome.
Increased levels of epoxide hydrolase in the prefrontal cortex were found in the brains of young mice whose mothers had suffered infection during pregnancy. Inhibiting epoxide hydrolase reverses cognitive and social deficits associated with neurodevelopmental disorders, such as ASD.
Researchers have identified specific potassium channel genes that are altered by alcohol addiction.
Findings could have major implications for future studies into motivation, addiction and decision making, researchers report.