PER2

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PER2

Featured Genetics Neurology Neuroscience

·August 19, 2021·5 min read

Disturbed Circadian Rhythm May Be Associated With Alzheimer’s Disease

Long-term circadian rhythm disruptions induce Alzheimer's disease-like pathology in rats, which can be reversed by administering fluoxetine. Additionally, elevated levels of amyloid beta and circadian rhythm disruptions can trigger each other, leading to the cascade of neurological symptoms of dementia.

This shows a clock and the structure of CK1

Featured Genetics Neuroscience Open Neuroscience Articles

·February 13, 2020·5 min read

Molecular switch mechanism explains how mutations shorten biological clocks

Study reveals how certain genetic mutations can shorten the timing of the circadian clock, making some people extreme "morning larks" because their internal clock operates on a 20-hour cycle, as opposed to a 24-hour cycle.

Featured Neuroscience Psychology

·September 26, 2019·3 min read

Link between stress and circadian clock health revealed

Stress makes the circadian clock tick faster and better.

Featured Genetics Neuroscience

·August 15, 2019·3 min read

Moderate to heavy drinking during pregnancy alters genes in newborns and mothers

POMC, a gene which regulates the stress response system, and PER2, a gene associated with circadian regulation, are altered in women who drank moderate-to-high amounts of alcohol during pregnancy and their newborns.

Featured Neuroscience

·June 14, 2018·5 min read

Early Birds Less Prone to Depression

A new study reports middle aged people who are early risers have a lower risk of developing depression.

Featured Genetics

·May 9, 2018·4 min read

Study Links Breast Cancer to Body’s Internal Clock

Researchers have found an association between the Per2 gene and breast cancer. The Per2 gene plays an important role in both the body's circadian clock and mammary gland development.

Image shows how CRY1 affects the circadian clock.

Featured Neuroscience

·December 22, 2016·4 min read

Controlling the Body Clock

Researchers present a new approach to creating genetic knock out mice to help investigate circadian rhythm.

Brain Cancer Featured Neuroscience

·July 29, 2016·5 min read

Why Working the Night Shift Can Pose a Cancer Risk

A new study reports on a link between circadian cell disruption and cancerous tumor growth.

Artistic panting of a cloch with a sleeping person in the center.

Featured Neuroscience

·October 3, 2015·4 min read

How The Body Keeps Ticking: Identifying the Mechanism That Regulates the Circadian Clock

Researchers have identified a molecular switch which helps regulate the circadian clock and allows the body to keep time.

This image shows the different sleep/eat cycles of the per2 deficient mice.

Featured Genetics

·May 22, 2014·3 min read

Genes Discovered Linking Circadian Clock with Eating Schedule

Mutations in a pair of genes, which normally help regulate eating scheduled and keep them in sync with daily sleep rhythms, may play a role in so called night eating syndrome.

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