Long-term circadian rhythm disruptions induce Alzheimer's disease-like pathology in rats, which can be reversed by administering fluoxetine. Additionally, elevated levels of amyloid beta and circadian rhythm disruptions can trigger each other, leading to the cascade of neurological symptoms of dementia.
Study reveals how certain genetic mutations can shorten the timing of the circadian clock, making some people extreme "morning larks" because their internal clock operates on a 20-hour cycle, as opposed to a 24-hour cycle.
Stress makes the circadian clock tick faster and better.
POMC, a gene which regulates the stress response system, and PER2, a gene associated with circadian regulation, are altered in women who drank moderate-to-high amounts of alcohol during pregnancy and their newborns.
Researchers have found an association between the Per2 gene and breast cancer. The Per2 gene plays an important role in both the body's circadian clock and mammary gland development.
A new study reports on a link between circadian cell disruption and cancerous tumor growth.
Researchers have identified a molecular switch which helps regulate the circadian clock and allows the body to keep time.
Mutations in a pair of genes, which normally help regulate eating scheduled and keep them in sync with daily sleep rhythms, may play a role in so called night eating syndrome.