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p53

·September 28, 2023·4 min read

Protein p53’s Role in Autism-like Behavior and Memory

Scientists have discovered a direct link between the protein p53 and autism-like behavior in mice. The researchers studied the effects of manipulating p53 levels in the mouse hippocampus.

Featured Genetics Neuroscience

·July 19, 2022·4 min read

Going to the Beach? Planning a Hike? Be Prepared: Men Will Be Much Hungrier!

In males, sun exposure activates the p53 protein which signals to the body to produce the appetite-associated ghrelin hormone. In women, estrogen blocks the interaction between p53 and ghrelin, reducing the urge to eat following sun exposure.

Featured Neurology Neuroscience

·August 26, 2021·4 min read

Restoring Chaperone Protein May Prevent Plaque Build-up in Alzheimer’s

Restoring levels of the DAXX protein prevents misfolding of proteins that drive Alzheimer's disease and other neurodegenerative diseases.

Featured Genetics Neuroscience

·September 12, 2018·3 min read

Aging May Be As Old As Life Itself

Researchers report that, at the molecular levels, aging may have originated at the beginning of the evolution of life. They suggest when it comes to genes, aging may not always be a negative trait, and may help an organism to survive.

Brain Cancer Featured Genetics Neurology Open Neuroscience Articles

·April 25, 2018·4 min read

Organoids Reveal how Deadly Brain Cancers Grow

Researchers use gene editing to generate aggressive glioblastoma multiforme brain tumors in the lab. The model, researchers say, could be used to track the progression of tumors and develop personalized therapies for patients.

Featured Genetics Neurology

·May 22, 2017·5 min read

Experimental Therapy for Immune Diseases Hits Achilles Heel of Activated T Cells

PPCA treatment shown to provide therapeutic benefit in mouse models of hemophagocytic lymphohistiocytosis and multiple sclerosis.

Brain Cancer Featured Neurology

·May 1, 2017·6 min read

Super Computer Assists in Search For Better Cancer Treatments

Researchers are turning to supercomputers in the quest to discover new treatments and targets for cancers.

Image shows neurons, cancer cells and mitochondria.

Brain Cancer Featured Neurology

·January 11, 2017·5 min read

Salmonella May Help Treat Brain Tumors

A strain of a bacteria commonly associated with food poisoning could prove an unlikely ally in the battle against glioblastoma brain cancer, a new study reports.

Featured Neurology Open Neuroscience Articles

·October 12, 2016·5 min read

Amplifying Regeneration of Spinal Nerve Cells

Researchers have been able to successfully boost the regeneration of mature nerve cells in the spinal cord of adult mice following spinal cord injury.