In males, sun exposure activates the p53 protein which signals to the body to produce the appetite-associated ghrelin hormone. In women, estrogen blocks the interaction between p53 and ghrelin, reducing the urge to eat following sun exposure.
Restoring levels of the DAXX protein prevents misfolding of proteins that drive Alzheimer's disease and other neurodegenerative diseases.
Researchers report that, at the molecular levels, aging may have originated at the beginning of the evolution of life. They suggest when it comes to genes, aging may not always be a negative trait, and may help an organism to survive.
Researchers use gene editing to generate aggressive glioblastoma multiforme brain tumors in the lab. The model, researchers say, could be used to track the progression of tumors and develop personalized therapies for patients.
PPCA treatment shown to provide therapeutic benefit in mouse models of hemophagocytic lymphohistiocytosis and multiple sclerosis.
Researchers are turning to supercomputers in the quest to discover new treatments and targets for cancers.
Researchers find high levels of progesterone can kill glioblastoma cells and inhibit brain tumor growth.