NF1

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NF1

This shows a child playing with building blocks

Autism Featured Neuroscience Open Neuroscience Articles

·July 7, 2020·4 min read

Sensory Neurons Outside the Brain Drive Autistic Social Behaviors

The loss of the protein neurofibromin 1 (NF1) in adult male flies resulted in social impairments. The deficits were traced back to a primary disruption in a small group of peripheral neurons which control external stimuli, including touch and smell, that communicate to the brain. Read More

Brain Cancer Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·May 1, 2020·4 min read

New targets for childhood brain tumors identified

Neurons and immune cells work together to promote tumor growth in neurofibromatosis type 1. Read More

Brain Cancer Featured Neurology Neuroscience

·June 3, 2019·4 min read

Immune cells determine how fast certain tumors grow

Immune cells can accelerate the growth of cancerous tumors in mouse models of NF1. Read More

Brain Cancer Featured Genetics Neurology

·August 14, 2017·3 min read

Gene Combinations That Cause Glioblastoma Brain Cancer Identified

CRISPR technology and advanced screening techniques allow researchers to comb through over 1500 genetic combinations to find multiple drivers of glioblastoma brain cancer. Read More

Featured Genetics Neuroscience Visual Neuroscience

·December 13, 2016·6 min read

Estrogen Increases Vision Loss Risk in Rare Genetic Disease

A new study suggests blocking estrogen may help preserve eyesight in girls with NF1. Read More

Brain Cancer Featured Genetics

·December 4, 2016·6 min read

Researchers Uncover More Genetic Links to Brain Cancer Cell Growth

Researchers believe their findings could lead to new targets for brain cancer therapies. Read More

Autism Featured Open Neuroscience Articles Psychology

·October 19, 2016·6 min read

Single Gene Linked to Some Cases of Autism

A new study reveals that a single gene may be linked to some cases of ASD. Read More

Featured Genetics Neuroscience Videos Open Neuroscience Articles

·September 12, 2014·3 min read

Zebrafish Model of a Learning and Memory Disorder Shows Better Way to Target Treatment

Researchers report the learning and memory deficits associated with neurofibromatosis are distinct features which require different treatment approaches. Read More

Neurons are shown. Caption describes it well.

Brain Cancer Featured Neurology

·October 22, 2012·3 min read

Aggressive Brain Tumors Can Originate from a Range of Nervous System Cells

Scientists have long believed that glioblastoma multiforme, the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain or in neural stem cells. Researchers found that the tumors can originate from other types of differentiated cells in the nervous system, including cortical neurons. Read More

Brain Cancer Featured Genetics Neurology

·August 29, 2012·5 min read

Could a Cancer Drug Potentially Prevent Learning Disabilities in Some Kids?

U-M scientists stop abnormal brain cell growth in mice with neurofibromatosis using experimental tumor drug, make new discoveries in neural stem cells. Read More

Brain Cancer Featured Genetics Neurology

·July 9, 2012·3 min read

Pediatric Tumors Traced to Stem Cells in Developing Brain

Scientists showed in mice that disabling a gene linked to a common pediatric tumor disorder, neurofibromatosis type 1 (NF1), made stem cells from one part of the brain proliferate rapidly. But the same genetic deficit had no effect on stem cells from another brain region. Read More

Genetics Neuroethics

·March 9, 2012·2 min read

Genetic Manipulation Boosts Growth of Brain Cells Linked to Learning, Enhances Effects of Antidepressants

Southwestern Medical Center investigators have identified a genetic manipulation that increases the development of neurons in the brain during aging... Read More

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