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neuropsychopharmacology

Featured Neurology Neuroscience Psychology

·April 20, 2024·7 min read

Risks of Antipsychotic Use in Dementia Patients

A new study revealed significant risks associated with antipsychotic use in dementia patients, including increased chances of stroke, heart failure, pneumonia, and other serious conditions. The research analyzed data from 173,910 dementia patients in England, tracking those prescribed antipsychotics post-diagnosis against those who were not.

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Featured Neuroscience Psychology

·February 12, 2024·7 min read

Ketamine’s Effects Diverge by Sex

Ketamine's effects on depression and pain, and its interaction with opioid pathways, significantly differ between sexes. In a detailed rat study, the team found that blocking opioid receptors nullified ketamine's impact only in males, suggesting a complex interplay between ketamine, opioid systems, and sex hormones.

Featured Neuroscience Psychology

·February 21, 2023·5 min read

Medication Targeting Brain Stress Response May Help Cardiovascular Symptoms of Alcohol Withdrawal

Prazosin, an FDA-approved medication for the treatment of hypertension may help to prevent relapse in people with cardiovascular and behavioral symptoms of alcohol withdrawal, a new study reports.

Featured Neuroscience Psychology

·February 16, 2023·3 min read

Receptor Location Matters for Psychedelic Drug Effects

Location bias may explain how psychedelic medications work. Researchers found that engaging serotonin 2A receptors inside neurons promotes the growth of new connections, but engaging the same receptor on the outside of a neuron does not. The findings may guide the development of new psychoplastogens to treat a range of disorders including depression and PTSD.

Autism Featured Neuroscience Open Neuroscience Articles

·February 14, 2023·4 min read

Drug Shown to Alleviate Autism-Associated Behavior

A newly developed drug that blocks sodium channels in the cell membrane that can reverse MYT1L failure alleviates social behavior deficits in mouse models of ASD.

Featured Neuroscience Psychology

·January 15, 2023·5 min read

Old Antipsychotic Drugs May Offer New Option to Treat Type 2 Diabetes

Diphenylbutylpiperidines (DPBPs), an older class of antipsychotic medications can effectively be repurposed to help treat type 2 diabetes, a new study reports.

Featured Neuroscience Open Neuroscience Articles Psychology

·January 6, 2023·7 min read

Blood Pressure Drug Holds Promise for Treating PTSD

Clonidine, an FDA-approved medication commonly prescribed to treat blood-pressure disorders and ADHD, shows promise in mitigating the effects of PTSD.

Featured Neuroscience Psychology

·December 30, 2022·4 min read

Ketamine Found to Increase Brain Noise

By inhibiting NMDA receptors, ketamine increases noise to gamma frequencies in one layer of the thalamic nucleus and one lay of the somatosensory cortex. Findings suggest psychosis may be triggered by an increase in background noise impairing thalamocortical neurons which may be caused by a malfunction in NMDA receptors affecting the balance of inhibition and excitation in the brain.

Featured Neuroscience Open Neuroscience Articles Psychology

·December 9, 2022·4 min read

A Better Understanding of How the Most Commonly Used ADHD Medication Works

Study reveals how methylphenidate interacts with cognitive control networks and attention behaviors. Methylphenidate changes spontaneous neural activity in reward and cognitive control systems in children with ADHD. The changes result in more stable sustained attention.

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Featured Neuroscience

·December 2, 2022·4 min read

How Ketamine Acts as a ‘Switch’ in the Brain

Ketamine alters neural activity in the cerebral cortex, silencing normally active neurons and activating neurons that are normally inactive. The ketamine activity-induced "switch" in brain regions associated with depression may help explain its treatment effects.

This shows Vyvanse (Lisdexamfetamine) 70mg capsules

Featured Neuroscience Psychology

·November 17, 2022·5 min read

ADHD Medication for Amphetamine Addiction Linked to Reduced Risk of Hospitalization and Death

Lisdexamfetamine (Vyvanse), a medication commonly used to treat ADHD, lowers the risk of hospitalization and death for those with amphetamine use disorder.

Featured Neuroscience Psychology

·May 20, 2022·3 min read

Novel Preclinical Drug Could Have Potential to Combat Depression, Brain Injury, and Cognitive Disorders

A preclinical drug that inhibits the kinase enzyme Cdk5 may have the potential to treat depression, brain injuries, and disorders associated with cognitive impairment.

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neuropsychopharmacology

Risks of Antipsychotic Use in Dementia Patients

Ketamine’s Effects Diverge by Sex

Medication Targeting Brain Stress Response May Help Cardiovascular Symptoms of Alcohol Withdrawal

Receptor Location Matters for Psychedelic Drug Effects

Old Antipsychotic Drugs May Offer New Option to Treat Type 2 Diabetes

Blood Pressure Drug Holds Promise for Treating PTSD

Ketamine Found to Increase Brain Noise

A Better Understanding of How the Most Commonly Used ADHD Medication Works

How Ketamine Acts as a ‘Switch’ in the Brain

ADHD Medication for Amphetamine Addiction Linked to Reduced Risk of Hospitalization and Death

Novel Preclinical Drug Could Have Potential to Combat Depression, Brain Injury, and Cognitive Disorders

Frequent Snoring in Teens Linked to Behavior Issues

Toddlers Use Grammar Hints to Unlock the Meaning of New Words

Maternal Inflammation May Shape Offspring’s Alzheimer’s Risk

Low Confidence Drives Feedback-Seeking, Boosts Learning Outcomes

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