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neuropharmacology

·June 3, 2024·2 min read

Aspirin Eases Inflammation from Sleep Loss

Low-dose aspirin reduces inflammatory responses caused by sleep restriction. Compared to a placebo, aspirin lowered interleukin-6, COX-1/COX-2 cells, and C-reactive protein levels.

Featured Neuroscience Psychology

·June 3, 2024·3 min read

Ozempic May Reduce Alcohol Abuse Risk

Diabetes drugs Wegovy and Ozempic, containing semaglutide, significantly reduce the incidence and recurrence of alcohol-use disorder (AUD). Analyzing health records, researchers observed a 50% to 56% decrease in AUD among patients treated with semaglutide.

Featured Neuroscience

·May 31, 2024·3 min read

SSRIs Reveal New Potential Beyond Depression Treatment

A new study uncovers a key biological process targeted by SSRIs, suggesting new clinical applications. The study found that SSRIs affect membrane trafficking in cells, which might explain their broader effects. Remarkably, a single dose of fluvoxamine in mice enabled drug delivery across the blood-brain barrier. This discovery could lead to SSRIs aiding in the delivery of drugs for conditions like dementia.

Featured Neuroscience

·May 28, 2024·3 min read

Light-Activated Drug Induces Sleep by Targeting Brain Receptors

Researchers developed a light-sensitive drug that enhances adenosine activity in the brain, inducing sleep in mice without genetic modification. This innovation overcomes the limitations of conventional photosensitive drugs, offering precise control over sleep and motivation via A2A receptors.

Featured Neuroscience

·May 24, 2024·6 min read

Psilocybin Induces Brain Hyperconnectivity, Enhancing Mystical Experiences

Psilocybin, the active compound in magic mushrooms, initiates a pattern of dynamic hyperconnectivity in the brain. This brain state is linked to the ego-modifying effects and feelings of oceanic boundlessness commonly reported during psychedelic experiences.

Featured Neurology Neuroscience

·May 21, 2024·8 min read

Ketamine’s Effect on Brain Activity Revealed

A new computational model reveals how ketamine, a widely used anesthetic and antidepressant, affects brain activity. By simulating the drug's interaction with NMDA receptors, the model explains how ketamine alters neuronal firing patterns, leading to altered states of consciousness and potential therapeutic benefits for depression.

Featured Neuroscience

·May 16, 2024·6 min read

GLP-1 and NMDA Targeted Weight-Loss Drug Shows Promise

Researchers have developed a novel weight-loss drug that combines GLP-1 with molecules targeting NMDA receptors in the brain. This "Trojan Horse" approach allows the drug to specifically target the appetite control center, leading to significant weight loss in mice.

This shows a woman in a doctor's office.

Featured Neurology Neuroscience

·May 7, 2024·5 min read

Addiction Medication Offers New Hope for Long COVID Patients

Researchers identified a potential treatment for long COVID by restoring the function of ion channels in immune cells using low-dose Naltrexone. This discovery, detailed in Frontiers in Immunology, mirrors earlier findings with chronic fatigue syndrome (ME/CFS) patients, suggesting a common pathophysiological thread between the two conditions.

This shows a brain, RNA and cancer cells.

Brain Cancer Featured Neurology Neuroscience

·May 1, 2024·8 min read

Novel mRNA Vaccine Shows Promise Against Deadly Brain Cancer

Researchers introduced a new mRNA cancer vaccine that rapidly activates the immune system against glioblastoma, the deadliest form of brain tumor. This new vaccine technology, which mimics the structure of COVID-19 vaccines but incorporates personalized tumor cells and a complex cluster delivery system, has shown promising results in preclinical models and an initial human trial involving four adult patients.

Featured Neurology Neuroscience Psychology

·April 20, 2024·7 min read

Risks of Antipsychotic Use in Dementia Patients

A new study revealed significant risks associated with antipsychotic use in dementia patients, including increased chances of stroke, heart failure, pneumonia, and other serious conditions. The research analyzed data from 173,910 dementia patients in England, tracking those prescribed antipsychotics post-diagnosis against those who were not.

Featured Neurology Neuroscience

·April 18, 2024·6 min read

CBD’s Neuroprotective Properties Explored

Summary: Cannabinol (CBN), a cannabinoid derived from cannabis, offers neuroprotective properties that could treat neurological disorders like Alzheimer’s, Parkinson’s, and...

Featured Neurology Neuroscience

·April 18, 2024·4 min read

Treatment Relieves Chronic Lyme Disease’s Neurological Symptoms

Fibroblast growth factor receptor inhibitors, commonly used in cancer treatment, could effectively reduce neurological symptoms in patients with post-treatment Lyme disease syndrome. The study shows these inhibitors can decrease inflammation and cell death in brain and nerve tissues affected by Lyme disease.

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neuropharmacology

Aspirin Eases Inflammation from Sleep Loss

Ozempic May Reduce Alcohol Abuse Risk

SSRIs Reveal New Potential Beyond Depression Treatment

Light-Activated Drug Induces Sleep by Targeting Brain Receptors

Psilocybin Induces Brain Hyperconnectivity, Enhancing Mystical Experiences

Ketamine’s Effect on Brain Activity Revealed

GLP-1 and NMDA Targeted Weight-Loss Drug Shows Promise

Addiction Medication Offers New Hope for Long COVID Patients

Novel mRNA Vaccine Shows Promise Against Deadly Brain Cancer

Risks of Antipsychotic Use in Dementia Patients

CBD’s Neuroprotective Properties Explored

Treatment Relieves Chronic Lyme Disease’s Neurological Symptoms

LLMs and Math Combine to Map Human Decision-Making

Sleep Apnea’s Main Symptom Is Also its Cause

Zero-Computational Path to High-Resolution Robotic Touch

Zebrafish Brain Features Mammalian-Like Sensory Sorting

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