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neuropharmacology

·April 18, 2024·4 min read

Treatment Relieves Chronic Lyme Disease’s Neurological Symptoms

Fibroblast growth factor receptor inhibitors, commonly used in cancer treatment, could effectively reduce neurological symptoms in patients with post-treatment Lyme disease syndrome. The study shows these inhibitors can decrease inflammation and cell death in brain and nerve tissues affected by Lyme disease.

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Featured Neurology Neuroscience

·April 17, 2024·5 min read

AI Revolutionizes Hunt for Parkinson’s Treatments

Researchers employed AI to fast-track the discovery of treatments for Parkinson's disease. They utilized machine learning techniques to screen millions of compounds and successfully identified five promising candidates that prevent the harmful clumping of alpha-synuclein, a key protein in Parkinson’s pathology.

Featured Neurology Neuroscience

·April 16, 2024·5 min read

HIV Drugs May Reduce Alzheimer’s Risk

Common HIV drugs could reduce the incidence of Alzheimer’s disease (AD). Utilizing anonymized prescription data from over 225,000 individuals, the study found that HIV-positive patients taking reverse transcriptase (RT) inhibitors showed a significantly lower rate of AD compared to the general population.

Featured Neurology Neuroscience

·April 16, 2024·4 min read

Monoclonal Antibody Slows Rapid Motor Decline in Parkinson’s

Prasinezumab, a monoclonal antibody targeting alpha-synuclein aggregation, shows promise in slowing motor deterioration in rapidly progressing Parkinson's disease (PD), according to an exploratory analysis from the phase 2 PASADENA clinical trial. While there are currently no disease-modifying treatments for PD, prasinezumab offers a potential breakthrough by specifically binding to aggregated alpha-synuclein, a key driver of PD pathology.

This shows a pregnant woman looking at pills.

Autism Featured Neuroscience

·April 9, 2024·5 min read

Acetaminophen in Pregnancy Not Linked to Autism, ADHD Risk

A comprehensive study involving over 2.4 million Swedish children has debunked the notion that acetaminophen use during pregnancy increases the risk of autism, ADHD, and intellectual disability in offspring. The research employed a novel sibling comparison method to eliminate confounding familial and environmental factors, revealing no increased risk of neurodevelopmental disorders among siblings exposed to acetaminophen prenatally versus those who were not.

Featured Neurology Neuroscience

·April 4, 2024·7 min read

Fecal Bacteria Transplant May Improve Parkinson’s Symptoms

A new clinical trial revealed fecal microbiota transplantation (FMT) as a potential new treatment for Parkinson’s disease (PD), showing significant improvement in motor symptoms. The study explores the connection between the gut microbiome and Parkinson's, finding that patients with PD often exhibit altered gut bacteria and increased intestinal inflammation.

This shows a doctor looking at brain scans.

Featured Neurology Neuroscience

·April 3, 2024·6 min read

Immunotherapy Shows Promise as Alzheimer’s Treatment

Researchers unveiled a novel approach to combat Alzheimer’s disease by activating microglia, the brain's immune cells, to devour amyloid beta plaques, a hallmark of the condition. This study highlights the potential of using immunotherapy to not only tackle Alzheimer’s but also other neurodegenerative diseases characterized by harmful protein accumulations.

Featured Neuroscience Psychology

·March 29, 2024·5 min read

Compound May Curb Alcohol Dependence

The compound LY2444296, which blocks the kappa opioid receptor, significantly reduces alcohol consumption in animal models of alcohol dependence. This study suggests LY2444296 could be a breakthrough in treating alcohol use disorder (AUD) by targeting the brain's KOP system, implicated in addiction and withdrawal symptoms.

Featured Neurology Neuroscience

·March 22, 2024·3 min read

CaMKII Can Be Regulated to Mitigate Alzheimer’s

The CaMKII protein, critical in brain and heart function, can be regulated to mitigate Alzheimer’s and heart conditions using three types of drug inhibitors. Their findings, published in Cell Reports, reveal that these inhibitors allow for precise assessments of CaMKII's roles, providing a valuable tool for scientists across various disciplines.

Featured Neuroscience

·March 18, 2024·4 min read

Exercise in a Pill? Breakthrough Mimics Workout Benefits

Researchers are developing compounds that simulate the benefits of physical exercise, potentially offering new treatments for muscle atrophy, heart failure, and neurodegenerative diseases. The compound SLU-PP-332 and its derivatives activate key proteins involved in exercise-induced muscle growth and metabolism.

Featured Neurology Neuroscience

·March 5, 2024·5 min read

Viagra Shows Potential As Alzheimer’s Treatment

Researchers identified sildenafil, known commercially as Viagra, as a promising candidate for treating Alzheimer's disease. Leveraging artificial intelligence the team analyzed vast amounts of data, including insurance claims and brain cell observations, to highlight sildenafil's potential benefits in reducing Alzheimer's prevalence and neurotoxic proteins.

Featured Neurology Neuroscience Psychology

·March 4, 2024·4 min read

How Impulse Control Disorders Alter Processing of Risky Decisions

A novel study explores how Parkinson's disease patients, particularly those with impulse control disorders (ICD) induced by dopaminergic medications, process the outcomes of risky decisions.

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neuropharmacology

Treatment Relieves Chronic Lyme Disease’s Neurological Symptoms

AI Revolutionizes Hunt for Parkinson’s Treatments

HIV Drugs May Reduce Alzheimer’s Risk

Monoclonal Antibody Slows Rapid Motor Decline in Parkinson’s

Acetaminophen in Pregnancy Not Linked to Autism, ADHD Risk

Fecal Bacteria Transplant May Improve Parkinson’s Symptoms

Immunotherapy Shows Promise as Alzheimer’s Treatment

Compound May Curb Alcohol Dependence

CaMKII Can Be Regulated to Mitigate Alzheimer’s

Exercise in a Pill? Breakthrough Mimics Workout Benefits

Viagra Shows Potential As Alzheimer’s Treatment

How Impulse Control Disorders Alter Processing of Risky Decisions

NFL Players Face Fourfold Increase in Neurodegenerative Mortality

Eye Movements Form a Unique Gaze Fingerprint

1,000-Subject Trial Maps Brain Aging in the Real World

ATP Platform Adaptive Trial Speeds Up Dementia Research

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