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neurogenesis

·May 22, 2025·6 min read

CRISPR Delivers RNA to Repair Neurons Right Where It’s Needed

Researchers have developed a new CRISPR-based technology that transports RNA to exact locations within neurons, where it can trigger repair and regrowth—offering hope for treating neurological diseases and injuries. Unlike traditional CRISPR tools that edit DNA, this system repurposes CRISPR-Cas13 to act like a “mailman,” carrying RNA to damaged sites using built-in molecular zip codes.

Featured Neuroscience

·May 9, 2025·3 min read

Oxygen Boost Sparks Early Brain Growth

A new study reveals that raising oxygen tension during weeks four to six of brain organoid development significantly promotes neurogenesis, guided by the oxygen-binding protein neuroglobin. Using cerebral organoids and cutting-edge imaging, researchers monitored internal oxygen levels and linked their changes to key stages in early brain development.

Featured Genetics Neurology Neuroscience

·April 11, 2025·6 min read

Hidden Neural Stem Cells May Hold Key to Brain Regeneration

Scientists have identified a previously unknown type of neural stem cell (pNSC) that exists outside the brain and spinal cord, overturning decades of neuroscience dogma. These peripheral neural stem cells, discovered in tissues like the lung and tail of mice, share key properties with brain-derived neural stem cells, including the ability to self-renew and differentiate into neurons.

This shows an AI representation of stem cells.

Featured Genetics Neuroscience

·February 8, 2025·5 min read

Stem Cells in the Brain Use Childlike Signals to Trigger Regeneration

Scientists have discovered that neural stem cells (NSCs) receive constant feedback from their daughter cells, influencing whether they remain dormant or activate to form new neurons and glia. This parent-child relationship helps regulate brain regeneration and repair.

Featured Neurology Neuroscience

·January 7, 2025·4 min read

Unlocking Spinal Cord Regeneration: Astrocytes Lead the Way

Spinal cord injuries (SCI) are challenging to treat due to the limited regenerative capacity of the central nervous system. A new study reveals that while ependymal cells in the spinal cord show minimal repair potential, astrocytes can transdifferentiate into oligodendrocytes, aiding in remyelination.

Featured Neuroscience

·December 5, 2024·5 min read

Adult Neurogenesis Fuels Verbal Learning and Memory

Adult neurogenesis, the creation of new brain cells, supports verbal learning and memory. Using brain tissue from epilepsy patients, researchers discovered a direct link between fewer immature brain cells and cognitive decline, particularly in verbal learning and memory.

Featured Genetics Neuroscience

·November 27, 2024·4 min read

Key Protein Found to Guide Neural Development and Cell Identity

Researchers have uncovered the crucial role of a protein subunit, INST10, in guiding pluripotent stem cells toward becoming neural cells during early development. The study found that diminished INST10 levels caused cells to lose neural identity and shift toward other fates, such as mesenchymal or intestinal cells.

Featured Neuroscience

·November 12, 2024·8 min read

Exercise Spurs Nerve Growth Through Biochemical and Physical Impact

Researchers found that exercise promotes neuron growth through both biochemical signals (myokines) and physical stretching. Muscle cells, when contracted, release myokines that boost neuron growth and maturity.

Featured Genetics Neuroscience

·October 24, 2024·6 min read

Yamanaka Factors Can Reverse Neuronal Aging

Yamanaka factors can reverse aging in brain neurons, improving synaptic connections, metabolism, and protecting against neurodegenerative diseases like Alzheimer's. Researchers introduced the Yamanaka factors into neurons of adult mice, finding that this process rejuvenated the cells without negative side effects, even enhancing motor and social behaviors.

Featured Neuroscience

·October 2, 2024·6 min read

Targeting Glucose May Spark Neurogenesis

Neural stem cells, which create new neurons in the brain, become less active with age due to elevated glucose levels. Researchers found that by knocking out the glucose transporter gene GLUT4 in older mice, they could significantly increase the production of new neurons.

Featured Neurology Neuroscience

·July 8, 2024·3 min read

Glial Cells Reprogrammed to Neurons for Brain Repair

Researchers have discovered how glial cells can be reprogrammed into neurons through epigenetic modifications, offering hope for treating neurological disorders. This reprogramming involves complex molecular mechanisms, including the transcription factor Neurogenin2 and the newly identified protein YingYang1, which opens chromatin for reprogramming. The study reveals how coordinated epigenome changes drive this process, potentially leading to new therapies for brain injury and neurodegenerative diseases.

Featured Neuroscience Psychology

·May 20, 2024·6 min read

Exercise Aids Memory Erasure in PTSD

Increased neuron formation in the hippocampus, stimulated by exercise or genetic manipulation, helps mice forget traumatic or drug-associated memories. This process involves rewiring neural circuits, disrupting the recall of fear memories. These findings offer potential new approaches for treating mental health conditions like PTSD and drug addiction.

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neurogenesis

CRISPR Delivers RNA to Repair Neurons Right Where It’s Needed

Oxygen Boost Sparks Early Brain Growth

Hidden Neural Stem Cells May Hold Key to Brain Regeneration

Stem Cells in the Brain Use Childlike Signals to Trigger Regeneration

Unlocking Spinal Cord Regeneration: Astrocytes Lead the Way

Adult Neurogenesis Fuels Verbal Learning and Memory

Key Protein Found to Guide Neural Development and Cell Identity

Exercise Spurs Nerve Growth Through Biochemical and Physical Impact

Yamanaka Factors Can Reverse Neuronal Aging

Targeting Glucose May Spark Neurogenesis

Glial Cells Reprogrammed to Neurons for Brain Repair

Exercise Aids Memory Erasure in PTSD

Disrupted Neuronal Microexons Drive Hyperarousal and Insomnia

AI Intelligence Is Not Consciousness

Autism Mutations Converge on Shared Early Brain Pathways

Rotating Spiral Brain Waves Act as a Space-and-Time Clock

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