Study reveals how neurons and glial cells contribute to drive neurodegeneration following brain injury.
Ketamine's rapid action as an antidepressant is a result of increasing the activity of a small number of newborn neurons, which are part of ongoing neurogenesis in the brain.
Researchers used optogenetics techniques to stimulate specific brain areas to increase neurogenesis and the production of neural stem cells to improve memory, cognition, and emotional processing in animal models.
INSR, a protein essential for insulin activity, plays a critical role in stem cell longevity. Additionally, inactivating INSR in glioblastoma brain cancer stem cells inhibits the growth of primitive tumor forming cells.
Study identified a complete series of ten factors that regulate the development of neurons in a fly's visual system, shedding light on the order in which these neurons develop.
Oleic acid produced in the brain is an essential regulator of processes that enable memory, learning, and mood regulation. Oleic acid, which is abundant in olive oil, also promoted neurogenesis and increases cell proliferation.
Hippocampal neurogenesis and cognitive function were improved in aging mice by destroying senescent cells in the aging stem cell niche.
Harnessing the power of "dancing molecules", researchers have developed a new injectable therapy that repairs tissue damage and reverses paralysis in mouse models. Within four weeks of receiving the injection, paralyzed mice regained the ability to walk.
Fenofibrate, an FDA-approved drug commonly used to treat high cholesterol, activated support cells around sensory neurons in mouse models of spinal cord injury, helping them regrow twice as fast as a placebo.
Mouse study reveals chronic stress affects neurogenesis in the dentate gyrus.
Diet and exercise can influence hippocampal neurogenesis, researchers say. Poor nutrition and lack of exercise have detrimental effects on hippocampal neurogenesis, increasing the risk for dementia.
Gut microbes that metabolize tryptophan secrete indoles that stimulate the development of new neurons in the adult brain.
