FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·January 20, 2022·6 min readOld Neurons Can Block Neurogenesis in MiceHippocampal neurogenesis and cognitive function were improved in aging mice by destroying senescent cells in the aging stem cell niche.Read More
FeaturedNeurologyNeuroscienceNeuroscience Videos·November 11, 2021·7 min readInjectable Therapy Reverses Paralysis in Mice with Spinal Cord InjuriesHarnessing the power of "dancing molecules", researchers have developed a new injectable therapy that repairs tissue damage and reverses paralysis in mouse models. Within four weeks of receiving the injection, paralyzed mice regained the ability to walk.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·October 19, 2021·5 min readDrug Helps Sensory Neurons Regrow in the Mouse Central Nervous SystemFenofibrate, an FDA-approved drug commonly used to treat high cholesterol, activated support cells around sensory neurons in mouse models of spinal cord injury, helping them regrow twice as fast as a placebo.Read More
FeaturedNeurosciencePsychology·September 22, 2021·3 min readSecond-Hand Psychological Stress Can Lead to DepressionMouse study reveals chronic stress affects neurogenesis in the dentate gyrus.Read More
FeaturedNeurologyNeuroscience·August 17, 2021·4 min readLack of Exercise and Poor Nutrition Could Increase the Risk of Diseases Like DementiaDiet and exercise can influence hippocampal neurogenesis, researchers say. Poor nutrition and lack of exercise have detrimental effects on hippocampal neurogenesis, increasing the risk for dementia.Read More
FeaturedNeuroscience·June 28, 2021·3 min readGut Microbe Secreted Molecule Linked to Formation of New Nerve Cells in Adult BrainGut microbes that metabolize tryptophan secrete indoles that stimulate the development of new neurons in the adult brain.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·June 7, 2021·3 min readMolecule Critical to Functional Brain Rejuvenation IdentifiedTET1, a newly identified molecule appears to play a key role in myelin repair. The findings could have implications for the treatment of a range of neurodegenerative diseases, including multiple sclerosis.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·May 30, 2021·3 min readIntermittent Fasting Improves Long Term MemoryMouse study reveals intermittent fasting improves long-term memory retention and promotes hippocampal neurogenesis. The findings could help to slow cognitive decline in older adults.Read More
FeaturedNeurologyNeuroscience·May 25, 2021·3 min read‘Rejuvenating’ the Alzheimer’s BrainMicroRNA-132 regulates neurogenesis in the hippocampus, according to both mouse and human tissue studies. Restoring levels of microRNA-132 in mouse models of Alzheimer's disease reduces neurogenetic deficits and restores cognitive abilities, researchers say.Read More
FeaturedGeneticsNeurologyNeuroscience·May 20, 2021·4 min readHow Injured Nerves Stop Themselves From HealingAt the site of injury, nerves release a protein called CXCL12 which attracts growing nerve fibers and keeps them trapped in place. This prevents the nerve fibers from growing in the correct direction to bridge the injury site.Read More
FeaturedNeuroscience·May 17, 2021·5 min readInsulin Is Necessary For Repairing Olfactory NeuronsFollowing injury or damage, insulin plays a key role in the maturation and regeneration of immature olfactory sensory neurons.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·March 23, 2021·4 min readParkinson’s Gene May Impair How New Neurons Are Made Throughout Our LifetimePINK1, a gene associated with Parkinson's disease, is not just responsible for the premature death of dopaminergic neurons, it also plays a key role in the neurogenesis of dopamine neurons throughout life.Read More
