Parkinson's patients have reduced acylated-ghrelin to unacylated-ghrelin ratios in their blood. Lower levels of unacylated-ghrelin have been associated with a reduced ability to generate new neurons and memory impairments. Read More
Researchers have identified a network of genes in Zebrafish that regulate the process of determining whether certain neurons will regenerate. Read More
Axon regeneration and dramatic improvements in functional recovery occurred when lactate was applied to damaged neural tissue. Treatment with lactate also significantly improved locomotion and restored some walking capability in mouse models of SCI. Read More
During pregnancy, the maternal environment has a dominant influence on the length of the neurogenic period and the number of upper-layer neurons produced. The study reveals a link between the maternal environment and embryonic cortical neurogenesis in-vitro. Read More
Prenatal diet could increase the risk of unhealthy eating and obesity in the offspring, a new study reports. Pregnant mice fed high omega-6 and low omega-3 diets were more likely to have offspring that were more inclined to consume hyper-caloric foods, increasing their risk of obesity. Read More
Transposable elements team up with evolutionary recent neurons to influence differentiation and physiological function of neurons in brain development. Read More
Mitochondria regulate how neural stem cells become neurons during brain development. The findings may help explain how humans developed larger brains during evolution and how mitochondrial defects lead to some neurodevelopmental disorders. Read More
Neurons created as a result of adult neurogenesis mature for longer and grow larger than those created during infancy. Findings suggest adult-born neurons may have a more powerful function than those created during infancy and may play a critical role in neuroplasticity. Read More
Making two different changes to a single messenger protein, researchers were able to inhibit lung cancer growth and promote neurogenesis. Read More
Hippocampal adult-born neurons are responsible for memory consolidation during REM sleep. Read More
Adult born neurons are essential for synaptic structural remodeling and memory consolidation during REM sleep, a new mouse study found. Read More
LIN28, a molecule that regulates cell growth could help in the treatment of spinal cord injury and optic nerve damage. When expressed above normal levels, the molecule fuels axon growth in mice with injury, enabling the body to repair damaged nerves. Read More
