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neurodegeneration

·April 7, 2022·4 min read

Brainstem Atrophy Is Linked to Extrapyramidal Symptoms in Frontotemporal Dementia

Patients who suffer from frontotemporal dementia with extrapyramidal symptoms have brainstem atrophy and reduced metabolic activity in specific brain regions compared to those with FTD without extrapyramidal symptoms.

This shows the woman with the implant walking with the assistance of a nurse

Featured Neuroscience

·April 6, 2022·2 min read

Electronic Implant Reactivates Spinal-Cord Nerves of a Patient With Neurodegenerative Disease

An innovative new system that includes electronic implants directly onto the spinal cord reactivates neurons that control blood pressure, allowing a patient with multiple system atrophy-parkinsonian type (MSA-P) to retain consciousness when she is in an upright position.

This shows a brain made up of jigsaw pieces

Featured Neurology Neuroscience

·March 21, 2022·2 min read

Mapping the Brain for Early Alzheimer’s Detection

A new study aims to map the brain from the onset of Alzheimer's disease through the different progressive stages via neuroimaging data to identify novel biomarkers associated with the disease at different stages.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 19, 2022·5 min read

New Strategy Reduces Brain Damage in PSP, Alzheimer’s, and Related Disorders in Mice

Alpha2-NKA, a protein that drives toxicity in astrocytes, was discovered in higher levels of brain samples from people who died of PSP, Alzheimer's and other tau-related neurodegenerative disorders. Treatment with an FDA-approved drug called digoxin may suppress the inflamed astrocytes and halt disease progression for those with tauopathy disorders.

Featured Neurology Neuroscience Open Neuroscience Articles

·February 8, 2022·3 min read

A Protein Present in the Gums May Help Prevent Alzheimer’s

Recent studies have found a link between P. gingivalis, bacteria that plays a significant role in periodontal disease, and an increased risk of Alzheimer's disease. A new study reports SCPPPQ1, a protein expressed in the cells of the junctional epithelium, has antibacterial potential and could slow, or even destroy P. gingivalis.

Featured Genetics Neurology Neuroscience

·January 19, 2022·6 min read

Astrocyte Studies Reveal Harmful Changes in Amyotrophic Lateral Sclerosis

In patients with ALS, astrocytes within the brain become pro-inflammatory and tend to lose their protective function, resulting in changes in the ability to uptake glutamate.

This shows a man standing at a blackboard covered in math equations

Featured Neuroscience

·January 2, 2022·4 min read

Academic Education Can Positively Affect Aging of the Brain

Older adults with an academic background showed lower increases of signs of brain degeneration than those who were less educated, a new study reports.

This shows a drawing of a head, intestines and microbes

Featured Neurology Neuroscience

·December 21, 2021·4 min read

Gut-Derived Metabolites That Play a Role in Neurodegeneration Identified

Researchers have identified high levels of three gut-produced toxic metabolites in plasma and cerebrospinal fluid samples of patients with multiple sclerosis.

Featured Neurology Neuroscience

·November 8, 2021·4 min read

Increased Fats and Protein Could Provide Diagnosis in Lewy Body Dementia

Increased ceramide levels in the brain may be a unique feature of all types of Lewy body dementias, including LBD associated with Parkinson's disease.

Featured Neurology Neuroscience Open Neuroscience Articles

·October 22, 2021·4 min read

Fat Cells Found to Play a Central Role in Cognitive Decline and Neurodegeneration

A new study reveals how adipocytes, or fat cells, play a role in cognitive decline and increased neurodegeneration risks. Using genetically modified mouse models, researchers found oxidative stress through exposure to a Western diet increased the production of inflammatory cytokines confined to adipocytes and altered protein markers of memory and cognition in the hippocampus.

Featured Neurology Neuroscience Open Neuroscience Articles

·October 19, 2021·4 min read

Viral Infections Could Promote Neurodegeneration

Some viral infections could increase intercellular spreading of protein aggregates associated with neurodegenerative disorders, increasing the risk for developing Alzheimer's, Parkinson's, and other neurodegenerative diseases.

Featured Neurology Neuroscience

·September 13, 2021·1 min read

Researchers Shed New Light on Molecular Mechanisms in Brain Diseases

Study reveals the molecular mechanisms implicated in the regulation of toxic proteins in neurodegenerative diseases like Alzheimer's and Parkinson's disease.

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neurodegeneration

Brainstem Atrophy Is Linked to Extrapyramidal Symptoms in Frontotemporal Dementia

Electronic Implant Reactivates Spinal-Cord Nerves of a Patient With Neurodegenerative Disease

Mapping the Brain for Early Alzheimer’s Detection

New Strategy Reduces Brain Damage in PSP, Alzheimer’s, and Related Disorders in Mice

A Protein Present in the Gums May Help Prevent Alzheimer’s

Astrocyte Studies Reveal Harmful Changes in Amyotrophic Lateral Sclerosis

Academic Education Can Positively Affect Aging of the Brain

Gut-Derived Metabolites That Play a Role in Neurodegeneration Identified

Increased Fats and Protein Could Provide Diagnosis in Lewy Body Dementia

Fat Cells Found to Play a Central Role in Cognitive Decline and Neurodegeneration

Viral Infections Could Promote Neurodegeneration

Researchers Shed New Light on Molecular Mechanisms in Brain Diseases

Brain’s Parenting Hub Redirects Care Toward Peers

70-Year-Old Drug Could Stop Epilepsy Seizures

Vision Rescued: How Stem Cells “Rehabilitate” the Dying Eye

Tubulin May Prevent Against Alzheimer’s and Parkinson’s

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