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neurodegeneration

Featured Genetics Neurology Neuroscience

·April 20, 2022·5 min read

Single-Cell DNA Sequencing Offers a New Angle on the Causes of Alzheimer’s Disease

An abundance of newly acquired mutations in the mutations that occur at an accelerated speed is a telling pattern of Alzheimer's disease, researchers report.

This shows different drawings of neurons from healthy to diseased

Featured Neurology Neuroscience Open Neuroscience Articles

·April 19, 2022·4 min read

Research Team Affirms Useful Blood Biomarker for Group of Brain Disorders in New Study

Study confirms neurofilament light is a useful blood-based biomarker for frontotemporal dementia, PSP, and primary progressive aphasia.

This shows the outline of a head and a question mark

Featured Genetics Neurology Neuroscience

·April 13, 2022·4 min read

Why Certain Brain Neurons Are Vulnerable to Degeneration

Wolframin-expressing excitatory neurons (WFS1) are more vulnerable in the entorhinal cortex.WFS1 may reduce tau-pathology and neurodegeneration via the regulation of stress response to the abnormal buildup of tau aggregates and the downstream protein degradation pathway.

This shows a depiction of a brain made up of rainbow colored lines

Featured Genetics Neurology Neuroscience

·April 13, 2022·5 min read

Novel Root Cause of Tau-Induced Neurodegeneration Discovered

mRNA decay may facilitate tau-induced damage to the brain and associated apoptosis that contributes to a range of neurodegenerative disorders. Researchers found the mechanism can be altered pharmacologically, providing a new target for the development of therapeutics to prevent or slow the progression of some neurodegenerative disorders.

Featured Neurology Neuroscience

·April 7, 2022·4 min read

Brainstem Atrophy Is Linked to Extrapyramidal Symptoms in Frontotemporal Dementia

Patients who suffer from frontotemporal dementia with extrapyramidal symptoms have brainstem atrophy and reduced metabolic activity in specific brain regions compared to those with FTD without extrapyramidal symptoms.

This shows the woman with the implant walking with the assistance of a nurse

Featured Neuroscience

·April 6, 2022·2 min read

Electronic Implant Reactivates Spinal-Cord Nerves of a Patient With Neurodegenerative Disease

An innovative new system that includes electronic implants directly onto the spinal cord reactivates neurons that control blood pressure, allowing a patient with multiple system atrophy-parkinsonian type (MSA-P) to retain consciousness when she is in an upright position.

This shows a brain made up of jigsaw pieces

Featured Neurology Neuroscience

·March 21, 2022·2 min read

Mapping the Brain for Early Alzheimer’s Detection

A new study aims to map the brain from the onset of Alzheimer's disease through the different progressive stages via neuroimaging data to identify novel biomarkers associated with the disease at different stages.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 19, 2022·5 min read

New Strategy Reduces Brain Damage in PSP, Alzheimer’s, and Related Disorders in Mice

Alpha2-NKA, a protein that drives toxicity in astrocytes, was discovered in higher levels of brain samples from people who died of PSP, Alzheimer's and other tau-related neurodegenerative disorders. Treatment with an FDA-approved drug called digoxin may suppress the inflamed astrocytes and halt disease progression for those with tauopathy disorders.

Featured Neurology Neuroscience Open Neuroscience Articles

·February 8, 2022·3 min read

A Protein Present in the Gums May Help Prevent Alzheimer’s

Recent studies have found a link between P. gingivalis, bacteria that plays a significant role in periodontal disease, and an increased risk of Alzheimer's disease. A new study reports SCPPPQ1, a protein expressed in the cells of the junctional epithelium, has antibacterial potential and could slow, or even destroy P. gingivalis.

Featured Genetics Neurology Neuroscience

·January 19, 2022·6 min read

Astrocyte Studies Reveal Harmful Changes in Amyotrophic Lateral Sclerosis

In patients with ALS, astrocytes within the brain become pro-inflammatory and tend to lose their protective function, resulting in changes in the ability to uptake glutamate.

This shows a man standing at a blackboard covered in math equations

Featured Neuroscience

·January 2, 2022·4 min read

Academic Education Can Positively Affect Aging of the Brain

Older adults with an academic background showed lower increases of signs of brain degeneration than those who were less educated, a new study reports.

This shows a drawing of a head, intestines and microbes

Featured Neurology Neuroscience

·December 21, 2021·4 min read

Gut-Derived Metabolites That Play a Role in Neurodegeneration Identified

Researchers have identified high levels of three gut-produced toxic metabolites in plasma and cerebrospinal fluid samples of patients with multiple sclerosis.

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neurodegeneration

Single-Cell DNA Sequencing Offers a New Angle on the Causes of Alzheimer’s Disease

Research Team Affirms Useful Blood Biomarker for Group of Brain Disorders in New Study

Why Certain Brain Neurons Are Vulnerable to Degeneration

Novel Root Cause of Tau-Induced Neurodegeneration Discovered

Brainstem Atrophy Is Linked to Extrapyramidal Symptoms in Frontotemporal Dementia

Electronic Implant Reactivates Spinal-Cord Nerves of a Patient With Neurodegenerative Disease

Mapping the Brain for Early Alzheimer’s Detection

New Strategy Reduces Brain Damage in PSP, Alzheimer’s, and Related Disorders in Mice

A Protein Present in the Gums May Help Prevent Alzheimer’s

Astrocyte Studies Reveal Harmful Changes in Amyotrophic Lateral Sclerosis

Academic Education Can Positively Affect Aging of the Brain

Gut-Derived Metabolites That Play a Role in Neurodegeneration Identified

How Severe Illness During Pregnancy Alters Fetal Brain Development

Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

Youth Protein TIMP2 Restores Immune Function in the Aging Brain

Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

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